PPT-Gas Chromatography-Mass

Spectrometry Dr Erica Zarate Auckland Science Analytical Services Mass Spectrometry 12 June 2015 Gas chromatography Mass Spectrometry Robust More reproducible than LCMS Can be fully automated. and Linkage Analysis. Natasha E. Zachara Ph.D.. nzachara@jhmi.edu. What questions might you ask?. What . monosaccharides. modify my protein?. What oligosaccharides modify my protein?. How are these sugars linked to each other?. chromatographyand.  mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, environmental analysis, explosives investigation, and identification of unknown samples. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification.. BP Schools Link. Looking for Chemicals which are hidden . BP Schools Link – . Creative Chromatography. 8. In some products the chemicals we want to measure can be hidden / masked by other bigger molecules. Gas Chromatograph. Gas chromatography (GC). , is a common type of . chromatography . used in . analytical . chemistry for separating and analyzing compounds that can be vaporized without decomposition. . When chemica. l evidence is collected at a crime scene, it must be run through an instrument.. These instruments are designed to identify the chemical by comparing it with a database or known properties.. Instrumental Analysis Instrumentation Paper Chromatography GC – Gas Chromatography HPLC- High Performance Liquid Chromatography IR – Infrared Spectroscopy UV-Vis Spectroscopy MS – Mass Spectrometry ALONG WITH . H/D. EXCHANGE TO CHARACTERIZE . ANTIPLATELET DRUG DEGRADATION PATHWAYS.. A case report. .. B. ernard Do*, . Fatma . Amrani. , . Philippe-Henri . Secrétanand. . Najet. . Yagoubi. *Hospital Pharmacist . chromatographyand.  mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, environmental analysis, explosives investigation, and identification of unknown samples. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification.. Function. Components. Common uses. Chromatographic resolution. Sensitivity. Function. Separation of volatile organic compounds. Volatile – when heated, VOCs undergo a phase transition into intact gas-phase species. Gas Chromatography Mass Spectrometry Dr Kersti Karu email: kersti.karu@ucl.ac.uk Office number: Room LG 11 Recommended Textbooks: - “ Analytical Chemistry ” , G. D. Christian, P. K. Dasgupta , All right reserved 123 International Journal of Agriculture Innovations and Research Volume 6 , Issue 1 , ISSN (Online) 2319 - 1473 Gas Chromatography : Principles , Advantages and Applications i Mikhail Tswett. Russian Botanist. (1872-1919). . Mikhail Tswett. invented chromatography in 1901 during his . research on plant pigments. . . He used the technique to separate various plant pigments such as . A. . technique for the separation of a mixture by passing it in solution or suspension through a medium in which the components move at . different . rates. .. Principle. It is based on the principle of the partition of the solute between two phases/solvents. .. Different substances, carried by a gas, travel through a column packed with a solid material at different speeds, so that they become separated the number of peaks on the output of a gas chromatograph shows the number of compounds .