PPT-Inherited bone marrow failure syndromes

Josu de la Fuente Departments of Paediatrics and Haematology Imperial College London 25 of paediatric and 10 of young adult patient presenting with aplastic anaemia Fanconi Anaemia Median age of presentation 7 years of age. By. . SOMESHWAR.K. M.PHARM.. II - SEMESTER . . . Department of Pharmaceutics. University College of Pharmaceutical Sciences,. KAKATIYA UNIVERSITY. How would you describe yourself? . Make a list of 5 characteristics…. Essential Questions. How are inherited traits different from learned behaviors?. Vocabulary to Know:. Inherited trait. Offspring. Traits. and. Learned Behaviors. 4.10 Science concepts. . The student knows that organisms undergo similar life processes and have structures that help them survive within their environment. The student is expected to: . By: . Cammie’s. Corner. Inherited traits. Every living thing has . traits. . that make it . unique. . . A . trait. is a quality or characteristic of a living . thing. Physical . features. The color of an animals’ fur . THROMBOPHILIA. Defects in physiologic anticoagulant pathways. Increased production of procoagulant. Antithrombin deficiency. Protein C deficiency. Protein S deficiency. Factor V . Leiden. Prothrombin G20210A gene mutation. Brian Boulmay. , . MD. Bone Marrow Failure . Ineffective marrow-poeisis is the final endpoint of many diseases. . Congenital. Acquired . Genetic. Environmental or iatrogenic causes. Congenital marrow failure can present at any age.. Lauren . Cosolo. , RN, BScN, MN. Outline. Review bone marrow failure and disease. Discuss . Myelodysplastic. syndrome, pathophysiology, clinical presentation, diagnosis, treatment. Discuss Aplastic Anemia, . Department of Pathology and Laboratory Medicine. Located 2-3655. Hours of Operation: . 8am-6pm M-F . 8am-5pm Saturday. . Follow a . Bone. Marrow from collection to diagnosis. Laboratory. Testing. Pancytopenia. Pancytopenia. . is a reduction in the blood count of all the major. cell lines – red cells, white cells and platelets. It has several causes. which . can be broadly divided into . decreased bone marrow . 1. Diaphysis. Shaft or body of a long bone . Main part of the bone. Houses the marrow, composed of compact bone. Provides the strength and support functions for the bone . Periosteum. Tough connective tissue covering that surrounds the shaft of the bone. Ventricular arrhythmia with structural abnormality. Idiopathic ventricular arrhythmia. Inherited arrhythmia syndromes. Idiopathic Ventricular Arrhythmia. Inherited Arrhythmia Syndromes. Inherited Arrhythmia Syndromes. 59 Procedure Name of the Fellow: Successfully completed a bone marrow biopsy simulation course ? YES NO N/A I. Procedure Preparation: □ List indications . □ Check labs, medication Inherited Traits. Are part of a creature’s genetic structure. We are born with these traits. They depend on the genetic code of our parents and grandparents. Make a list of some traits you can think of that are inherited.. ®. Hematopoietic Stem Cells (HSCs) are capable of developing into any blood cell lineage. They develop in the bone marrow.. A small percentage of HSCs interacted with the . endosteal. niche, SNO cells, and osteoblasts..