PPT-Amino Acids as Protein Building Blocks

Proteins are naturallyoccurring biopolymers comprised of amino acids The biological function of proteins is inherent in their three dimensional structure All the information required for correct folding of the protein into its functional . B.2. Properties of 2-amino acids . (B.2.2). Zwitterion. (dipolar) . amino acids contain both acidic and basic groups in the same molecule . therefore, are . amphoteric. in nature (capable of behaving as acids or bases). Unit objectives:. Identify amino acid classifications based on nutritional use and chemical properties of side chains. Describe the primary, secondary, tertiary and quaternary structures of proteins. Stolen and Edited by: Keith King. Objectives . Review central dogma of molecular biology. . Discuss type of protein.. Assess amino acids.. Demonstrate folding proteins.. protein folding video. Review – Central Dogma of Molecular Biology . A nutrient found in all living things. It contains nitrogen and is responsible for the formation, maintenance, and repair of the body’s tissues/ It can also be used for energy. CHNO. Amino acids . Polypeptides . are chains of amino acids linked together by condensation reactions. the main, or only, component in proteins. Some proteins are composed of only one polypeptide chain, while others are made of 2 or more. 6. 6.1 Differentiate . between essential amino acids and nonessential amino acids.. 6.2 List . the functions of protein in the body.. 6.3 List . the steps for protein digestion and absorption in the body. . for . life.. . The importance of proteins was recognized by chemists in the early 19th century, including Swedish chemist . Jöns. Jacob Berzelius. , who in 1838 coined the term . protein. , a word derived from the Greek . Peptide bond formation. : . α-carboxyl group of one amino acid (with side chain R1) forms a covalent peptide bond with α-amino group of another amino acid . ( . with the side chain R2) by removal of a molecule of water. The result is : Dipeptide ( i.e. Two amino acids linked by one peptide bond). By the same way, the dipeptide can then forms a second peptide bond with a third amino acid (with side chain R3) to give . Protein. Builds and repairs body tissue. Provides some energy. There are 4 calories per gram of protein. Protein. Composed of chains of amino acids. Common Amino Acids. Alanine. Glycine. Isoleucine. Leucine. Amino acids play central roles both as building blocks of proteins and as intermediates in metabolism. . The 20 amino acids that are found within proteins convey a vast array of chemical versatility. . CLASSIFICATION AND PROPERTIES  Amino acids are organic compounds containing amine [ - NH 2 ] carboxyl [ - COOH] side chain [R group]  The major key elements if amino acids are carbon, hydrogen (N. utritionally. . Essential & Nutritionally Non Essential Amino . Acids ). Lecture : 4. Dr. . Shaimaa. . Munther. Nutritionally Essential & Nutritionally Non Essential Amino Acids . Introduction: . imino. acid.” . Figure 5: Comparison of the secondary amino group found in proline with the primary amino group found in other amino acids such as alanine.. 2. Proline: . Proline differs from other amino acids in that its side chain and amino N form a rigid, five -member red ring structure (Figure 5). Proline, then, has a secondary (rather than a primary) amino group. It is frequently referred to as an “. BSc 3. rd. year . AMINO ACIDS. C. lassification of amino acids . Classification according to nature of side chain. PREPARATION OF AMINO ACIDS. 1. Gabriel Phthalimide synthesis. 2. Strecker’s synthesis.