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Slide1
Understanding Basic Genetic Genealogy and My DNA Results
Olivia Fordiani
Slide2The content of this video, as well as the thoughts, views, and opinions expressed herein belong solely to the creator and do not necessarily reflect the views of FamilySearch International and RootsTech.
Slide3Will my siblings have different DNA and ethnicity results than I have?
Who should I test in my family?
What does
cM
on my cousin matches page stand for?
How can
cM
help me figure out relationships?
How is a chromosome browser helpful to me?
Should I contact all of my matches, even the ones that I share only a little bit of DNA with?
Have you ever wondered…
Slide4Basics of Inheritance
Humans have 22 pairs of autosomes and one pair of sex chromosomes (XX for female, XY for male).
The genes on each chromosome specify certain traits like hair color or blood type. Each person has two variations of each gene, called alleles. One of the mother’s two alleles and one of the father’s two alleles is passed to the child so the child ends up with two alleles as well.
https://en.wikipedia.org/wiki/Gene
https://www.ncbi.nlm.nih.gov/books/NBK541156/
Male
https://support.ancestry.com/s/article/Unexpected-Ethnicity-Results
Slide5Chromosome Recombination (Crossing Over)
One copy of chromosome from mom and one from dad
Chromosomes replicate to form sister chromatids
Maternal and paternal chromosomes separate into different daughter cells during Meiosis 1
Sister chromatids separate into different daughter cells during Meiosis 2
Recombination allows for
genetic variation and diversity
Why siblings don’t look the same
https://
www2.palomar.edu/anthro/biobasis/bio_3.htm
text=There%20are%208%2C324%2C608%20possible%20combinations,to%20thousands%20of%20different%20genes
#:~:.
https://www.genome.gov/genetics-glossary/Crossing-Over
Slide6Percentages
Inherited
by G
eneration
https://support.ancestry.com/s/article/Unexpected-Ethnicity-Results
Slide7https://isogg.org/wiki/Cousin_statistics
Slide8Should My Siblings Get Tested?
Slide9Slide10Centimorgans
(
cM
)
A
c
entimorgan is a unit of measurement used to measure genetic linkage or distance along a chromosome.The more
cMs
shared between two people, the more closely related they will be.
I share 74
cM
with my cousin, which means that’s the distance along a chromosome, or the amount of DNA we share. Our 74 shared
cM
are broken into segments on different parts of our chromosomes.
Slide11DNA Painter S
hared
Centimorgan
Project
Slide12https://dnapainter.com/tools/sharedcmv4
Slide13Autosomes are 22 of your 23 chromosomes that specify traits passed down
Chromosomes cross over and genes are recombined which allows for
genetic variation and
diversity
Because of recombination, siblings look different and have inherited DNA from distant ancestors you may not have inherited DNA from – test your siblings!
Test the oldest generation in your family
Centimorgans
show
how much shared DNA you have with a relative. You can use the amount of
cM
shared to figure out relationships using The Shared
Centimorgan
ProjectChromosome browsers allow you to visualize where you share DNA with your matchesIf two of your matches share DNA with you at the same place on your chromosome, you share a common ancestor – you are a triangulated match.
Be wary of matches at about 7
cM
or lower – they could be false matches!
Takeaways
Slide14Thank you for your time! Please feel free to reach out to me via LinkedIn, Facebook Messenger, or E-mail if you have further questions.
LinkedIn
: https://www.linkedin.com/in/olivia-fordiani/
Facebook
: https://www.facebook.com/olivia.fordiani
/
E-mail: livymay@gmail.com
Slide15