PPT-Group 2 Innate Lymphoid Cells in Nasal Polyposis

Whitney W Stevens MD PhD Atsushi Kato PhD Ann Allergy Asthma Immunol February 20211262110117 Group 2 Innate Lymphoid Cells in Nasal Polyposis Key Messages Type 2 cytokines interleukin IL4 IL5 and IL13 are highly elevated and play a critical role in the pathogenesis of chronic rhinosinusitis with nasal polyps. gene . expression. . Ronald S. . Veazey. , DVM, PhD. Division of Comparative Pathology. Tulane National Primate Research Center. Covington, Louisiana. Tulane University School of Medicine. New Orleans, Louisiana. Chapter 22. Functions of the Immune System. Destroy pathogens (organisms that cause disease). Detect and kill abnormal cells such as cancerous cells. Remove dead cells and debris from the body. Pathogens. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. 1. 33. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. Immunity. Nonspecific . immune . response – . Ch. 33. Aka . nonspecific . resistance. Clarence Lam, . Sanket. Patel, . Tairan. Yang, Narthaanan Srimurugathasan. PHM142 Fall 2016. Instructor: Dr. Jeffrey Henderson. Outline. Introduction and components of innate immunity. Differentiation from blood cells and mechanisms of phagocytosis. Nasal polyps are non-neoplastic masses of edematous nasal mucosa.. They are divided into two main types:. Ethmoidal. . Polypi. Antrochoanal. Polyp. They can also be presenting features of fungal sinusitis and . Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. 01.12.18. Tutorial Information. All content is presented in a question-answer format . (helpful . for making flashcards) . Answers to practice questions can be found in the slide notes . Lecture 2: Immune cells and organs. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Primary lymphoid tissue. : Bone marrow, Bursa of fabricius, Thymus.. Secondary lymphoid tissue. : Lymph node, Spleen.. Tertiary lymphoid tissue. : Mucosa-associated lymphoid tissue, Intra-epithelial lymphocytes.. Dr. . Bipin. Patel. introduction. INTRODUCTION. The term “immunity” is referred to the . resistance of an individual . towards . injury. caused by . microbial stimuli . (microorganisms & their products) & . Learning Objectives. Introduction to Immunity. Innate Immunity. Lymphoid Tissue. Introduction to Immunity. Immunitas. : Freedom from. Immunity is the ability of body to destroy potentially hazardous/harmful foreign substances, if entered in body, that is it provides FREEDOM from any foreign invader.. There are lots of . micoorganisms. that we . encounter everyday . through breathing, touching, and eating. . Most are detected and . destroyed within minutes or hours . by defense mechanisms that do not rely on the clonal expansion of antigen-specific lymhphocytes. . Organs and . cells. Peter Kelleher. Senior Lecturer, Imperial . College London, . Chelsea & Westminster . campus. Learning objectives . Illustrate the importance of immunology for human health..  .