PPT-Special Topics in Genomics

Nextgeneration Sequencing Work flow of conventional versus secondgeneration sequencing a With highthroughput shotgun Sanger sequencing genomic DNA is fragmented then cloned to a plasmid vector and used to transform E coli For each sequencing reaction a single bacterial colony is picked and plasmid DNA isolated Each cycle sequencing reaction takes place within a microliterscale volume generating a ladder of ddNTPterminated dyelabeled products which are subjected to highresolution electrophoretic separation within one of 96 or 384 capillaries in one run of a sequencing instrument As fluorescently labeled fragments of discrete sizes pass a detector the fourchannel emission spectrum is used to generate a sequencing trace . analyze . your data with a mouse click. Igor Makunin. i.makunin@uq.edu.au. QAAFI, UQ, April 8, 2015. Research. Computing. Centre. @ UQ. Genomics Virtual Laboratory. Genome scale experiments are relatively cheap and very popular. Whedon. Dr. David Lavery. Fall 2014. PH 308, M 600-900. “. We’d Do the Weird Stuff”: The Naughty Joss . Whedon. “We’d do the weird stuff”:. Joss . Whedon’s. Naughty Side. Thanks to. http://davidlavery.net/weird_stuff. Whedon. Dr. David Lavery. Fall 2014. PH 308, M 600-900. Special Topics in Film Studies: Joss . Whedon. Collaborating. Directing Other People’s Shows, . Cameoing. Whedon’s. collaborative nature has manifested itself outside of his own ‘verses in various ways. He has written for two comic book series, X-Men and . Whedon. Dr. David Lavery. Fall 2014. PH 308, M 600-900. . . Special Topics in Film Studies: Joss . Whedon. . . Special Topics in Film Studies: Joss . Whedon. Buffy Summers. Killed In: . Buffy the Vampire Slayer. Whedon. Dr. David Lavery. Fall 2014. PH . 308, . M 600-900. Special Topics in Film Studies: Joss . Whedon. . Buffy . as a Cult TV Show. Special Topics in Film Studies: Joss . Whedon. . Buffy . as a Cult TV Show. Bioinformatics and Genomics. Applications:. Personalized cancer medicines. Disease determination . Pathway Analysis. Biomarker Discovery . An Interesting Point. “One . article estimated that the output from genomics may soon dwarf data heavyweights such as . Dr. David Lavery, Fall 2016. Entities and Groups. Special Topics in Popular Culture, Fall 2016. Brotherhood without Banners. Special Topics in Popular Culture, Fall 2016. Children of the Forest. Special Topics in Popular Culture, Fall 2016. NGS analysis. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and . selection, . regulation, epigenomics, . disease. Manolis Kellis. MIT Computer Science & Artificial Intelligence Laboratory. Broad Institute of MIT and Harvard. Goal: A systems-level understanding of genomes and gene regulation:. What is Structural Genomics ?. Is the process of high-. throughtput. determination of 3-D structures of Biological macromolecules. What is the Goal of Structural Genomics ?. Provision of enough structural templates to facilitate homology modeling of most proteins.. “. User facility. providing high-throughput DNA sequencing & analysis in support of DOE missions in alternative . energy. , . carbon cycling . & . bioremediation. .”. Opened in 1999. ~240 UC Employees. July 201 MaeÕr ddogfen yma hefyd ar gael yn Gymraeg. This document is also available in Welsh. #$%&'!#%()$*+,-./!01232! 1 Genomics for Precision Medicine Strategy Executive Summary New genetic and g Bella Starling. Director of Public . Programmes. , CMFT. Wellcome. Trust Engagement Fellow. About me. Career. Scientist (neuroscience, genetics, stem cells). Science writer. Biomedical ethics. Public engagement, . Ian Green. Clinical Engagement and Education Business Manager. Strategy. Work undertaken by Genome One (part of the . Garvan. Institute). Work underway. Completion date . –. 17. th. , March 2017.