PPT-V8 – Genomics data Program for today:

Read mapping SNP calling SNP frequencies in 1000 Genomes data Isoforms of genes alternative splicing Noncanonical translation Removing sequence redundancy 1 V8 Processing of Biological Data. Bioinformatics and Genomics. Applications:. Personalized cancer medicines. Disease determination . Pathway Analysis. Biomarker Discovery . An Interesting Point. “One . article estimated that the output from genomics may soon dwarf data heavyweights such as . NGS analysis. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and . Melbourne Genomics Health Alliance. Clinic of the future: near and far. Melbourne Genomics Health Alliance. The (distant) future of genomics. Throughout life. 5. Prognosis. Treatment. Future disease. selection, . regulation, epigenomics, . disease. Manolis Kellis. MIT Computer Science & Artificial Intelligence Laboratory. Broad Institute of MIT and Harvard. Goal: A systems-level understanding of genomes and gene regulation:. February 6, 2013. Howard K. . Koh. , MD, MPH. Assistant Secretary for Health . U.S. Department of Health and Human Services . Progress Review Overview. Summarize the burden of Cancer in the U.S. and the role of Genomics . What is Structural Genomics ?. Is the process of high-. throughtput. determination of 3-D structures of Biological macromolecules. What is the Goal of Structural Genomics ?. Provision of enough structural templates to facilitate homology modeling of most proteins.. Alan . Christoffels. South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, South Africa, Secretariat: Public Health Alliance for Genomic Epidemiology. he genomics lifecyclefrom data creation, collection, and processing to storage and access.HIPAA Choose from 180+ HIPAA-eligible services on AWS to help you store, analyze, and share genomic data in a Heads of Medicines Agencies www.hma.eu An agency of the European Union European Medicines Agency www.ema.europa.eu GenomicsGenetics, Transcriptomicsand EpigeneticsubgroupreportDidier Meulendijks, Genomics and Society Nature (2014) “ …disorders not readily explained by standard tests can sometimes be diagnosed through genome sequencing and analysis.” The Origin of “Genomics& . Carl Pray. 1. Can advances in biology transform Asian agriculture? Challenges are large. Food production . Productivity growth . Crises – . Biological -Africa Swine Fever, corn stalk borer, fall armyworm, wheat rust. What . is . Functional. . Genomics?. RNA . Transcription/Gene. . Expression. Measuring Gene. . Expression. Microarrays. High-throughput. . Sequencing. Transcriptional. . Regulation. Transcription. . . Shawneequa L. Callier, JD, MA . Associate Professor. Clinical Research and Leadership. School of Medicine and Health Sciences. George Washington University. Special Volunteer. Center for Research on Genomics . Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and .