PPT-ALK in lung cancer: Past, present, and future

Gene Mutations in Lung Adenocarcinomas 17 years ago 25 chromosomal translocation in most anaplastic largecell nonHodgkins lymphomas which fused the NPM gene on chromosome 5q35 to ALK on chromosome 2p23 . Each year more people die of lung cancer than of colon breast and prostate canc ers combined Most lung cancers could be prevented because they are related to smoking or secondhand smoke or less often to exposure to radon or other environmental facto .. . Preliminary results. . Dimitra . Kerdidani. , . Vaso. . Karavana. , Sofia . Magkouta. , Aggeliki . Meligova. , Charis Roussos, Spyros . Zakynthinos. , Ioannis . Kalomenidis. , Maria Tsoumakidou. . Nathan Pennell, M.D., Ph.D.. September 6, 2014. Objectives. Discuss the role of chemotherapy in molecularly defined populations. Discuss the addition of chemo and/or bevacizumab (Avastin) to targeted therapy. Department of Earth Science and Engineering. Imperial College London. Meng-Che. Wu. meng-che.wu08@imperial.ac.uk. Jian. . Guo. Liu. j.g.liu@imperial.ac.uk. Outline. Background & Purpose. Method Development. What it is & what you need to know. What is lung cancer?. 2 types:. 1. Non-small cell lung cancer (NSCLC). 85% of cases. 2. Small cell lung cancer -10%-15% of all lung cancer cases. . Symptoms of lung cancer. By: Cindy . Stegman. RN BSN. Alverno. College MSN 621. Spring 2010. stegmacm@alverno.edu. How to navigate this tutorial:. To advance to next slide click on box. To advance to previous slide click on box. 1-4. The lifetime risk of occupational lung cancer. in Australia. School of Public Health, Curtin University. School of Public Health, University of Sydney. Department of Epidemiology and Preventive Medicine, Monash University. Project 1 – . Chris Amos. and James McKay. Project 2 – . Paul Brennan. and Mattias Johansson. Project 3 – . Rayjean Hung. Administrative Core – Chris Amos and Rayjean Hung. Biostatistics Core – . PGY-6. Pulmonary and Critical Care Fellow . GOALS. Lung Cancer Incidence & Mortality . Dealing with Incidental Found Nodules. You are responsible for all ED “un” necessary imaging . Lung . Cancer . of Lung Cancer . Wendi S Lee, MSN, RN, NP-C. Anne S Tsao, MD. Disclosure for . Ms. Lee. Consulting Agreement. Pfizer Inc. Disclosures for Dr Tsao. Advisory Committee. Ariad Pharmaceuticals Inc, AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, EMD Serono Inc, Genentech, Huron, Lilly, Merck, Novartis, Roche Laboratories Inc, Seattle Genetics, SELLAS Life Sciences, Takeda Oncology. Lung Cancer: Medical Aspects of Causation. Aneuploidy. Unlimited cell reproduction and failure of cell death. Animal Studies. Basic Toxicology. New Data on Causation. New Studies. New Statistics. Number of cases. Lara K. . Goudsouzian. , Ph.D.. Associate Professor of Biology. DeSales. University. Lara.goudsouzian@desales.edu. Melanoma. Melanocytes. Produce Melanin. Melanin is a dark pigment. The melanin travels in vesicles called . Department of Earth Science and Engineering. Imperial College London. Meng-Che. Wu. meng-che.wu08@imperial.ac.uk. Jian. . Guo. Liu. j.g.liu@imperial.ac.uk. Outline. Background & Purpose. Method Development. . 5. th. most commonly diagnosed cancer in Australia. 8.9% of new cancer diagnoses. In 2009: . 10,193 cases (. 6034 . men, 4159 women). Projection to . 2020.  . 13,640. Mortality. In 2010 most common cause of cancer death.