PPT-Antigens A. Immunogen A substance that induces a specific immune response.

B Antigen Ag A substance that reacts with the products of a specific immune response C Hapten A substance that is nonimmunogenic but which can react with the products of a specific immune response. 1. 34. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. Overview of Specific . (Adaptive) Immunity. Three major functions. recognize . nonself. T. h. e Specific Immune Response. OCR AS Biology – F212 – Module 2. Food & Health. Learning Objectives. Success Criteria. Understand the role of the specific immune system.. Understand the role of B and T Lymphocytes in fighting off pathogens.. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;. Types of Antigen. Complete Antigen: Substances which can induce antibody formation by themselves. . Haptens: substances which are unable to induce antibody formation on its own but can become immunogenic, i.e., capable of inducing antibodies, when covalently linked to proteins known as carrier proteins.. 1. Immunity: Two Intrinsic Defense Systems. Innate. (nonspecific) system responds quickly and consists of:. First line of defense. – skin and mucosa prevent entry of microorganisms. Second line of defense. Key attributes of immune system. 4 attributes that characterize the immune system as a whole. specificity. antigen-antibody specificity. diversity. react to millions of antigens. memory. rapid 2° response. Pathogen. Complement fixation. Pyrogens. Chemotaxis. Immunocompetant. Autograft. Isograft. Allograft. Xenograft. Hapten. Allergy/. hypersensitiviy. Immediate/acute hypersensitivity. Anaphylactic shock. Dr. Suzan Y.. Antigen. :. It s a substance that may be specifically bound by an antibody (. Ab. ) molecule or T cell receptors (TCR). When this binding lead to the activation of B cells or T cells ,this substance is known as . By: Dr. Suzan Y.. SPECIFIC COMPONENTS OF IMMUNE SYSTEM: LYMPHOCYTES. B-Lymphocytes (“B cells”). T- Lymphocytes (“T cells”). Natural Killer Cells (NK cells). Memory Cells. Suppressor Cells. They have different functions in specific immunity. ecognize. A. ttack. D. estroy . A. nd . R. emember. Bodies defense against pathogens. Immune System recognizes the identity of foreign substances. Antigens are found on the cells of all organisms and your body is able to identify your own cells and tell when a foreign cell has entered the system. Dr. Refif S. Al-. Shawk. . 2023. After reading this lecture, you should be able to: . Demonstrate how specific innate and adaptive immune response pathways and molecules are involved in the recognition and eradication of cancer cells. 3.2.2 All cells arise from other cells. INCLUDING the exam questions. TO HAND IN . Monday 4. th. January. Today we are covering from the specification:. What is the first line of . defence against disease?. Assist. Professor . Dr. Sinan Bahjat. M.B.Ch.B., M.Sc., F.I.B.M.S. . Antigens . are . molecules that react with antibodies. , . whereas immunogens . are . molecules . that induce an . immune response. Adaptive . Non-adaptive (. cell injury-----cell death). hypertrophy. Dysplasia. hyperplasia. neoplasia. Atrophy. Degeneration. Metaplasia. Necrosis, apoptosis. & gangrene. Reversible. Reversible* / Irreversible.