PPT-Antigens A. Immunogen A substance that induces a specific immune response.

B Antigen Ag A substance that reacts with the products of a specific immune response C Hapten A substance that is nonimmunogenic but which can react with the products of a specific immune response. 1. 34. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. Overview of Specific . (Adaptive) Immunity. Three major functions. recognize . nonself. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;. Defense from injury & illness. BIOL.10A . Describe the interactions that occur among systems that perform the . functions of . regulation, nutrient absorption, reproduction, and . defense from injury or illness . 1. Immunity: Two Intrinsic Defense Systems. Innate. (nonspecific) system responds quickly and consists of:. First line of defense. – skin and mucosa prevent entry of microorganisms. Second line of defense. Key attributes of immune system. 4 attributes that characterize the immune system as a whole. specificity. antigen-antibody specificity. diversity. react to millions of antigens. memory. rapid 2° response. Dr Rehma Dar. Assistant professor Pathology. Introduction to Immune System. Cell mediated vs Humoral Immunity. Hypersensitivity reactions. Autoimmune diseases. Transplant Rejection. Immunodeficiency states. Chapter 4. Introduction. Molecules recognized as “non-self” are antigens. Several mechanisms to protect itself . First level of protection include physical and biochemical-skin, acid in stomach. Second level of protection phagocytic cells, enzymes, and proteins. By . Dr. Sunita Mittal. Learning Objectives. To understand about acquired or adaptive immunity. Steps of humoral immune response. Steps of cellular immune response. Cytokines. Unwanted effects of immune system. By: Dr. Suzan Y.. SPECIFIC COMPONENTS OF IMMUNE SYSTEM: LYMPHOCYTES. B-Lymphocytes (“B cells”). T- Lymphocytes (“T cells”). Natural Killer Cells (NK cells). Memory Cells. Suppressor Cells. They have different functions in specific immunity. Dr. Refif S. Al-. Shawk. . 2022. . Cancer. is altered self cells that have escaped normal growth regulating mechanisms.. These cells give rise to clones of cells that can expand to a considerable size, producing a tumor, or . Transgenic mice from teratocarcinoma cells. https://. www.nobelprize.org. /prizes/medicine/2007/advanced-information/. genome. the mouse. to manipulate. using E.C. cells. Next:. What are some of the molecules recognized by this immune system?. Won Seok Song. 1. , Scott Wilson. 2. 1 . Johns Hopkins University, Department of Materials Science and Engineering, . 2. Johns Hopkins Medical Institutions. Introduction. Reaction Schema. Conclusion. Immunological unresponsiveness to self is referred to as . tolerance. or . self-tolerance. Very important to human health. How is this achieved?. -cells with receptors for self-antigens are destroyed in the thymus or bone marrow (central tolerance).