N ature of the Membrane Team Mawadda Al Naeeli Pat Cipriano Kim Conner Lopa Das Thea Edwards Tara Luke Facilitators Michelle Withers amp Karen York Goal Understand how the chemical structure of cell membranes underlie their function and adaptability ID: 708466
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Slide1
Membrane Fluidity : Its contribution to the Dynamic Nature of the Membrane
Team
Mawadda
Al-
Naeeli
Pat
Cipriano
, Kim Conner,
Lopa
Das,
Thea
Edwards, Tara Luke
Facilitators: Michelle Withers & Karen YorkSlide2
Goal
Understand how the chemical structure of cell membranes underlie their function and adaptability.
uSlide3
OutcomesUpon completion of this teachable unit the student will:
Explain how fluidity is changed by changes in the components of the membrane.
Predict how the lipid composition changes to maintain fluidity in extreme environments.
Practice drawing, reading and interpreting graphs.Slide4
ContextIntroductory BiologySlide5
Omega 3 Fatty Acids
Have you ever heard of Omega 3 fatty acids?
What are they?
What are some good sources of Omega 3 fatty acids?Slide6
C-C
C-HSlide7
Membrane proteins
Mouse cell
Human cell
http://www.youtube.com/watch?v=LicQb_SnCSI
Mixed proteins
after 1 hour
Hybrid cell
Fluid nature of lipid bilayer of cell membraneSlide8
Fluid
Unsaturated hydrocarbon
tails
Viscous
Saturated hydrocarbon tails
A
BSlide9
Decrease in fluidity with increase in cholesterol contentSlide10
Clicker Question
How does an increase in temperature affect membrane fluidity?
A. Increases fluidity
B. Decreases fluidity
C. No changeSlide11
Clicker Question
How does an increase in temperature affect membrane fluidity?
A. Increases fluidity
B. Decreases fluidity
C. No changeSlide12
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
Warm Water Fishes
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide13
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
↓
↑
↓
Warm Water Fishes
↑
↓
↑
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide14
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
↓
↓
Warm Water Fishes
↑
↑
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide15
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
↓
↑
↓
Warm Water Fishes
↑
↓
↑
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide16
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
↓
↑
Warm Water Fishes
↑
↓
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide17
Cholesterol
Unsaturated Fatty Acids
Saturated Fatty Acids
Cold Water Fishes
↓
↑
↓
Warm Water Fishes
↑
↓
↑
Consider cold water and warm water fishes.
How would membrane composition differ to maintain similar fluidity?
↑ ↓ --Slide18
Using your dataset, draw a graph that would show the effects of changing temperature on membrane cholesterol and omega-3 fatty acid (unsaturated) content.Slide19
Hassett R P , and Crockett E L J Exp Biol 2009;212:71-77
Relationship between cholesterol content and habitat temperature in copepods. Slide20
Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?
1. Membranes are more rigid
2. Membranes are more fluid
3. Membranes maintain the same fluiditySlide21
Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?
1. Membranes are more rigid
2. Membranes are more fluid
3. Membranes maintain the same fluidity
4. The organism dies
5. The organism survives
6. Membrane maintains function
7. Membrane loses function
8. Lipid composition changes
9. Lipid composition stays the sameSlide22
Which of the following would occur when considering the membrane of an organism
that…
(is exposed to colder temperatures than it normally experiences?)
(is exposed to warmer temperatures than it normally experiences?)
(is a
psychrophile
?)
(is a thermophile?)
(has a high level of cholesterol in its membrane?)
(has a low level of cholesterol in its membrane?)
(contains mostly saturated fats?)
(contains mostly unsaturated fats?)