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Membrane Fluidity : Its contribution to the Dynamic Membrane Fluidity : Its contribution to the Dynamic

Membrane Fluidity : Its contribution to the Dynamic - PowerPoint Presentation

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Membrane Fluidity : Its contribution to the Dynamic - PPT Presentation

N ature of the Membrane Team Mawadda Al Naeeli Pat Cipriano Kim Conner Lopa Das Thea Edwards Tara Luke Facilitators Michelle Withers amp Karen York Goal Understand how the chemical structure of cell membranes underlie their function and adaptability ID: 708466

membrane water fishes fluidity water membrane fluidity fishes fatty acids cold warm cholesterol unsaturated maintain composition saturated membranes similar

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Slide1

Membrane Fluidity : Its contribution to the Dynamic Nature of the Membrane

Team

Mawadda

Al-

Naeeli

Pat

Cipriano

, Kim Conner,

Lopa

Das,

Thea

Edwards, Tara Luke

Facilitators: Michelle Withers & Karen YorkSlide2

Goal

Understand how the chemical structure of cell membranes underlie their function and adaptability.

uSlide3

OutcomesUpon completion of this teachable unit the student will:

Explain how fluidity is changed by changes in the components of the membrane.

Predict how the lipid composition changes to maintain fluidity in extreme environments.

Practice drawing, reading and interpreting graphs.Slide4

ContextIntroductory BiologySlide5

Omega 3 Fatty Acids

Have you ever heard of Omega 3 fatty acids?

What are they?

What are some good sources of Omega 3 fatty acids?Slide6

C-C

C-HSlide7

Membrane proteins

Mouse cell

Human cell

http://www.youtube.com/watch?v=LicQb_SnCSI

Mixed proteins

after 1 hour

Hybrid cell

Fluid nature of lipid bilayer of cell membraneSlide8

Fluid

Unsaturated hydrocarbon

tails

Viscous

Saturated hydrocarbon tails

A

BSlide9

Decrease in fluidity with increase in cholesterol contentSlide10

Clicker Question

How does an increase in temperature affect membrane fluidity?

A. Increases fluidity

B. Decreases fluidity

C. No changeSlide11

Clicker Question

How does an increase in temperature affect membrane fluidity?

A. Increases fluidity

B. Decreases fluidity

C. No changeSlide12

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide13

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide14

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide15

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide16

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide17

Cholesterol

Unsaturated Fatty Acids

Saturated Fatty Acids

Cold Water Fishes

Warm Water Fishes

Consider cold water and warm water fishes.

How would membrane composition differ to maintain similar fluidity?

↑ ↓ --Slide18

Using your dataset, draw a graph that would show the effects of changing temperature on membrane cholesterol and omega-3 fatty acid (unsaturated) content.Slide19

Hassett R P , and Crockett E L J Exp Biol 2009;212:71-77

Relationship between cholesterol content and habitat temperature in copepods. Slide20

Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?

1. Membranes are more rigid

2. Membranes are more fluid

3. Membranes maintain the same fluiditySlide21

Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?

1. Membranes are more rigid

2. Membranes are more fluid

3. Membranes maintain the same fluidity

4. The organism dies

5. The organism survives

6. Membrane maintains function

7. Membrane loses function

8. Lipid composition changes

9. Lipid composition stays the sameSlide22

Which of the following would occur when considering the membrane of an organism

that…

(is exposed to colder temperatures than it normally experiences?)

(is exposed to warmer temperatures than it normally experiences?)

(is a

psychrophile

?)

(is a thermophile?)

(has a high level of cholesterol in its membrane?)

(has a low level of cholesterol in its membrane?)

(contains mostly saturated fats?)

(contains mostly unsaturated fats?)