PPT-Modulators (effectors) influence oxygen binding to hemoglobin:

Positive effectors stabilize the R state Oxygen Carbon monoxide CO Nitric oxide NO Hydrogen sulfide H 2 S Negative effectors stabilize the T state D 23Bisphosphoglycerate BPG. 11 Specifications are subject to change without notice HOLOEYE Photonics AG AlbertEinsteinStr 14 12489 Berlin Germany Phone 49 030 6392 3660 Fax 49 030 6392 3662 contactholoeyecom wwwholoeyecom HOLOEYE Corporation 1620 Fifth Avenue Suite 550 San Di Mara Atwood . Outline. Discovery of blood. Important tasks of blood. Why blood substitutes?. Some current developments and products. Risks and Benefits . Discovery of Blood Groups. (1868-1943 ) Karl Landsteiner . Hemoglobin. Hemoglobin is the protein molecule in red blood cells that carries oxygen from the lungs to the body's tissues and returns carbon dioxide from the tissues back to the lungs.. Hemoglobin. Hemoglobin (. Introduction. As you know…. It is tasteless, . ordorless. Supports combustion. Vital for life. May be mixed with other gases (He, CO2, N2, NO2). Comprises 21% of the . atmopheric. gas. Normally 80-100 mmHg in the blood, 100 in the lung, 40 in the venous blood. During cold periods pond-dwelling animals can increase the number of unsaturated fatty acids in their cell membranes while some plants make antifreeze proteins to prevent ice crystal formation in tissue.. H6.1 Define partial pressure. Dalton’s Law of partial pressure states that the total pressure exerted by a mixture of gasses is the sum of the pressures exerted independently by each gas in a mixture. Essential idea: Red blood cells are vital in the transport of respiratory gases. D.6 Transport of respiratory gases. Nature of science: . Scientists . have a role in informing the public—scientific research has led to a change in public perception of smoking. (5.1) . hemoglobin molecule using a technique called X-ray diffraction noted during his experiments that hemoglobin can be found in two different forms or shapes These different shapes depended on whether oxy Adult male: 4.6 – 6 million. Adult female: 4.2 – 5 million. Red blood cells are: . Tiny, flexible biconcave discs. Lacks a nucleus. Can bend when going through tiny capillaries. RBC’s are constantly manufactured. Describes the pressure of a particular gas within a mixture. Equals the total pressure times the fractional concentration of the particular gas, . according to Whose Law?. Partial Pressure. Concentration of gases in ambient air. Learning Objectives. ▪ . Different . Hemoglobin . variants. ▪ . Characteristics of . Hemoglobin . variants and . Hb. ▪. Different . Hemoglobin . combinations. Hemoglobin . V. ariants. There . must be . Svjetlana Kalanj Bognar (. svjetla. na.kalanj.bognar. @mef.hr. ). Myoglobin. . and. hemoglobin, . oxygen-binding. . proteins. evolutionary. . demands. . of. . multicellular. . organisms. . and. April 2018. Clinical Pathology fellowship program. Renal Handling of acid-base status: . How does the kidney help to maintain a normal amount of both H. +. and HCO. 3. -. ?. H. +. secretion. Reabsorption of HCO. Hb. ) have related, but different, roles in the body. Hemoglobin:. Found in red blood cells. Promotes diffusion of O. 2 . throughout the body (binds O. 2 . at lungs,. . releases at tissues). Myoglobin:.