PPT-Development of genomic evaluations for direct measures of health in U.S. Holsteins and

KL Parker Gaddis 1 ME Tooker 2 JR Wright 2 JH Megonigal Jr 1 JS Clay 3 JB Cole 2 and PM VanRaden 2 1 Council on Dairy Cattle Breeding Bowie Maryland USA. Known as the Measures Management System this system is composed of a set of business processes and decision crit eria that CMS funded me asure developers or contractors follow in the development impl ementation and maintenance of quality measures Me breed composition for crossbred U.S. dairy cattle . Introduction. Traditional evaluations are on all-breed base. Pedigree breed composition (PBC) has been computed, distributed, and used to calculate heterosis since we went to the all-breed model in . for innovation and social transformation through . Govt. -CSO partnerships. Naresh Singh. Director-General, Partnerships with Canadians Branch, CIDA.. The development context. Most development interventions are not only complicated they are also complex. Few are simple, such as digging wells in a community where the wells is all you have to account for. Most humanitarian assistance actions might be complicated but are not complex (they become increasingly complex as we move on the spectrum to long term reconstruction and development.). Breeding companies are continuing to adapt their protocols and young bull buying criteria accordingly. All of this has led a higher emphasis of marketing young bulls and to an increase in the use of young bulls in the United States. Simulation studies indicate that even more young bull should be used to optimize genetic gains. Similarly, use of heifers instead of cows as bull dams is recommended. . Early genomic theory. Nejati-Javaremi. et al (. 1997. ) tested use of genomic relationship matrix in BLUP. Meuwissen et al (. 2001. ) tested linear and nonlinear estimation of . haplotype. effects. economics. Assoc. Professor Oliver Rivero-Arias. Royal Statistical Society Seminar. RSS Primary Health Care Special Interest . Group. 18 June 2015. Mapping . non-preference onto preference-based PROMs. Comm. 301. Reasons for changes in SNP set. History. Single list created across breeds. Poor performing SNPs removed. SNP selection criteria changed. Updated assembly changed SNP locations. Additional QTLs as . A “big data” project of the . Animal Genomics and Improvement Laboratory (AGIL). AGIL mission. Discover and develop improved methods for the genetic and genomic evaluation of economically important traits of dairy animals and small ruminants. Abstract #461. Background - Crossbreeding. Harris and Johnson (2010) . used multibreed relationship matrix to obtain GEBVs in NZL. Olson et al (2010) . estimated MT multi-breed SNP effects and genomic breed composition. March 2012 AIPL Update Topics Genomics overview April 2012 changes Accounting for bias Selection index adjustments Cow adjustments Calving traits update Whole-genome selection Use many markers to track inheritance of chromosomal segments A “big data” project of the . Animal Genomics and Improvement Laboratory (AGIL). AGIL mission. Discover and develop improved methods for the genetic and genomic evaluation of economically important traits of dairy animals and small ruminants. George Wiggans, CDCB Technical Advisor. Highlights of U.S. system. Over half a million animals genotyped in 2016. 67% of AI breedings to genomic bulls. Genomic relationship between genotyped cows and marketed bulls available. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen. Popular bulls have 10,000+ progeny. biology – lessons from dairy cattle breeding. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen.