PPT-Cell Mediated Immunity (CMI)

Dr Amany Ballow Consultant Immunology Assistant professor KKUH General Lab Director MDLAB PhD Diploma BSHIMSC Objective To describe antigen recognition by T cells To describe the pathways involved in processing endogenous and exogenous antigens. General principles of host defense. Mechanisms . of host defense against different classes of microbes . Immune evasion by microbes . Injury caused by normally protective immune responses . Strategies for vaccines . Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. Reaves. KEY CONCEPT:. The immune systems consists of organs, cells, and molecules that fight infections. Many other tissues and systems help the immune system. Skin. is a physical barrier to infection. A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Adaptive (specific) Immunity. The general idea:. body . can recognize . specific. . invader and act to destroy . that specific invader.. Adaptive . immunity develops during an individual. ’. s lifetime.. Chaparral High School. What is immunology?. Very simply, it is the study of our body’s defense against infection and disease.. Even though we are constantly bombarded by microorganisms, we rarely become sick. Why?. By Peter Wickham. 1. MEd (TESOL) . University of Wollongong NSW Australia. BEd. Edith Cowan University WA Australia. 1974-7 & 1990-2004 . primary school teacher. , Australia. 1978-89 . field linguist . In short, it is safe to state that immunity refers to the rules and principles that govern diplomatic relations between states and other entities with legal personality within the international system.. Tony Serino, . Ph.D. .. Immunity: Topic Objectives. Be able to describe the multilevel defenses of the body.. Be able to describe the symptoms and triggers for inflammation.. Be able to define adaptive immunity, antibodies, antigens and . GENESIS. 1.Lymphoblast. :15-20 micrometer. Large nucleus with rarely more than 2 distinct. nucleoli. Cytoplasm is blue as a narrow rim around the. large nucleus. Prolymphocyte. :. Prolymphocyte. :. The more Effective FLU VACCINE PROBLEM. WHO Meeting. August 23, 2016. Source: Abbas, . Abul. K, Andrew H. . Lichtman. , and Shiv Pillai. . Cellular and Molecular Immunology. . Philadelphia: Saunders/Elsevier, 2010. Print. .  . Immunity . is defined as the capacity of the body to resist the pathogenic agents. It is the ability of the body to resist the entry of . different types of . foreign bodies like bacteria, . virus, . Department of Pathology. College of . Medicine. KSU. Lecture # 3/6. Foundation block. Teaching objectives. To describe antigen recognition by. T cells. . To describe the pathways involved in processing endogenous and exogenous . Its . how your body recognizes and defends itself against bacteria, viruses, and substances that appear foreign and harmful.. IMMUNE SYSTEM- . Its a network of tissues and organs containing cells that recognize foreign substances in the body and destroy .