PPT-HDL- Cholesterol Presented By

AssistLecturer Aseel Ghassan Daoud MSc in PharmacyClinical Laboratory Sciences What is HDL It is a high density lipoprotein which is one of the classes of lipoproteins that carry cholesterol in the blood. 1. What is Cholesterol?. A waxy substance – technically a sterol (unsaturated steroid alcohol). 75% of your cholesterol is made in your liver, the rest is absorbed from food. Cholesterol travels in particles called lipoproteins: high-density lipoproteins (HDL) and low-Density Lipoproteins (LDL). d. e. . determina. t. ion. Int. r. oduct. i. on:. T. r. i. gly. c. e. r. i. d. es. . a. r. e. . es. t. e. r. s. . of fatty. . ac. i. ds. . and. . a. r. e. . hydro. l. yzed. . to. . gly. c. e. Rachel . Randle. Clinical Scientist in-service HSST. Viapath Bedford Hospital. Dr W Wassif. Consultant . Chemical . Pathologist. Bedford Hospital. On behalf of National . Clinical Biochemistry Audit Group. Cholesterol is an essential lipid constituent of cell membranes. Cholesterol is a precursor of steroid hormones and of bile acids. Intermediates of cholesterol biosynthesis are required to make vitamin D and for posttranslational modification of membrane proteins. Plasma lipoproteins. Prof. Mamoun Ahram. Resources. This lecture. Lippincott’s Biochemistry, Ch. 18. Characteristics of lipoproteins. Lipoproteins function to . Solubilize and carry plasma lipids. Transport lipids to (and from) the tissues. Plasma lipids . 200 . Lipoproteins . 201 . Fatty acids . 200 . Disorders of lipid metabolism . 207 . Cholesterol . 201 . Investigation of hyperlipidaemias . 214 . FATTY ACIDS . Lipids play a critical role in almost all aspects of . What are the current perspectives?. Prof. . Erik . Stroes. Academic Medical Centre. Amsterdam, The Netherlands. Is There a Therapeutic Need. . Beyond LDL Lowering ?. 1. Heart Protection Study Collaborative Group.. Chole lipoproteins, which got their name because they’re made of fat (lipid) and proteins. The two types of lipoproteins that carry cholesterol to and from c ells are low - density lipoprotein, or into cardiovascular protection []. Furthermore, as some glucose-lowering medications have shown to increase the risk for major adverse cardiovascular events (MACE), regulatory agencies require that al steviol. , on high density lipoprotein biogenesis. Aimee Furlan. 1,2. , . Xiaohu. Mei. 2. , Haya Herscovitz. 2. Design Tech High School, 275 Oracle Pkwy, Redwood City, CA 94065. 1. ; . Department of Physiology and Biophysics, Boston University, 700 Albany St, Boston, MA 02118. Cardiovascular . Block. Dr. . Usman. . Ghani. Objectives. By the end of this lecture, the First Year students will be able to:. Correlate . the imbalance . in lipoprotein metabolism with the development of . The wider roles of HDL. HDL and Reverse Cholesterol Transport. Phospholipid. Glycosphingolipid. Cholesterol. Lipid Raft. Normal Cell Membrane. Membrane rafts are small (10–200 nm), . heterogeneous cholesterol & . Prof. Ulf . Landmesser. University Hospital Zürich. Zürich, . Switzerland. Acute coronary syndromes result most frequently from coronary plaques without significant stenosis. Plaque in mid RCA. Occluded RCA. , MD, FRCPC, FACP, CCD, ECNU.. Associate . Professor and Consultant . Medicine, Endocrinology. Department of Medicine, King Saud University. Lipid Transport. LPL/Apo C2. Rader DJ, Daugherty, A Nature 2008; 451:904-913 .