PPT-DNA STRUCTURE & FUNCTION

DNA stands for       D eoxyribo N ucleic A cid DNA is the genetic i nformation in every cell DNA holds the instructions for making proteins The sequence of nitrogen bases in DNA determines the traits of an organism. Cell/Developmental Biology I. Group Members. Kelly Hogan, Facilitator . Rita Graze. Matthew . Kearley. . Zheng-Hua. Ye. Xiaoyu. Zhang. Christine Sestero. Heather Tinsley. Learning Goal: . Understand . Nucleic Acids. What do we know already?. i. . The nucleic acids DNA and RNA are polymers of nucleotides. Nucleotides consist of 3 parts. A 5-carbon sugar – ribose or deoxyribose. A phosphate group (acidic & negatively-charged). 2.6 Structure of DNA & RNA. Understandings:. The nucleic acids DNA & RNA are polymers of nucleotides.. DNA differs from RNA in the # of strands normally present, the base composition & type of pentose.. Part II: Proteins & Nucleic Acids. The FOUR Classes of Large Biomolecules. All living things are made up of four classes of large biological molecules: . Carbohydrates . Lipids. Protein. N. ucleic Acids. The Structure and Function of Macromolecules Part II: Proteins & Nucleic Acids The FOUR Classes of Large Biomolecules All living things are made up of four classes of large biological molecules: Biology: Unit 6 Part 2. What is DNA?. DNA = Deoxyribonucleic Acid. Contains information needed for the cell’s growth and other activities.. Determines the inherited characteristics of an organism.. . Copyright © Houghton Mifflin Harcourt Publishing Company. Cracking the Code. Copyright © Houghton Mifflin Harcourt Publishing Company. What is DNA?. The genetic material in cells is contained in a molecule called deoxyribonucleic acid, or . The helical structure of . DNA. Formation of Nucleotides. Structure of polynucleotide polymer. Each base has its preferred . tautomeric. form. Purine. and . Pyrimidine. Base . tautomers. ; are frequent sources of errors during DNA synthesis. . Understanding DNA structure and replication is a prerequisite for understanding/using the principal tools of molecular biology . R. R. 0. R0. R0. 0. R0. R0. R. 0. R. RR. R0. 0. R0. 00. DNA: Structure & Replication. The Double Helix (DNA). Structural model:. Model proposed by Watson & Crick, 1953. Two sugar-phosphate strands, next to each other, but running in opposite directions.. Specific Hydrogen bonds. occur among bases from one chain to the other:. Chapter 16.1. Life. ’. s Operating Instructions. In 1953, James Watson and Francis Crick introduced an elegant double-helical model for the structure of deoxyribonucleic acid, or DNA. Hereditary information is encoded in DNA . histones. (50%). Five major . histones. ; H2A, H2B, H3, H4 and H1 highly basic (. Arg. and Lys >25%). Roger Kornberg in 1974; . Chromatin. is made up of repeating units called . nucleosomes. , each containing 200 . Mini whiteboards. Sweets for DNA model (see link to sheet on slide). Speakers. Practical ‘DNA your onions’: blender, knife, white tile, water bath (60. o. C), ice, thermometer, beakers, funnel, filter paper, syringe, boiling tube, glass rod, pipette, protease, washing up liquid, salt, 95% ice cold ethanol. . What is DNA?. DNA is a . Nucleic Acid in the nucleus. Polymer of . Nucleotides. Each nucleotide consists of. Deoxy. ribose (5-carbon sugar) . Phosphate group. a nitrogen-containing base. Four bases.