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Peanut Allergy Immunotherapy Peanut Allergy Immunotherapy

Peanut Allergy Immunotherapy - PowerPoint Presentation

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Uploaded On 2022-02-12

Peanut Allergy Immunotherapy - PPT Presentation

Peanut Allergy Immunotherapy Options Oral Immunotherapy PatientDisease Characteristics and Response to AR101 PatientDisease Characteristics and Response to AR101 Subgroup Analysis PatientDisease Characteristics and Response to AR101 Discussion ID: 908523

immunotherapy allergy ar101 real allergy immunotherapy real ar101 food survey cont world oit characteristics epit risk side qol safety

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Presentation Transcript

Slide1

Peanut Allergy Immunotherapy

Slide2

Slide3

Peanut Allergy

Slide4

Immunotherapy Options

Slide5

Oral Immunotherapy

Slide6

Patient/Disease Characteristics and Response to AR101

Slide7

Patient/Disease Characteristics and Response to AR101: Subgroup Analysis

Slide8

Patient/Disease Characteristics and Response to AR101: Discussion

Slide9

QoL Improvements With AR101 Treatment Beyond the First Year (ARC004): Design

Slide10

QoL Improvements With AR101 Treatment Beyond the First Year (ARC004): Demographics

Slide11

QoL Improvements With AR101 Treatment Beyond the First Year (ARC004): Results

Slide12

QoL Data in Clinical Practice

Slide13

Real-World Survey, OIT for Food Allergy: Practice Patterns

Slide14

Real-World Survey, OIT for Food Allergy: Practice Patterns (cont)

Slide15

Real-World Survey, OIT for Food Allergy:

Side-Effect Management

Slide16

Real-World Survey, OIT for Food Allergy:

Side-Effect Management (cont)

Slide17

Real-World Survey, OIT for Food Allergy:

Side-Effect Management (cont)

Slide18

Discussion: GI Side Effects

Slide19

Epicutaneous Immunotherapy

Slide20

REALISE (Real-Life Use and Safety of EPIT) Study

Background

Slide21

REALISE Study Design and Safety Data Collection

Slide22

REALISE Baseline Characteristics

Slide23

REALISEBaseline Characteristics (cont)

Slide24

REALISELocal Skin Reactions Over Time

Slide25

REALISETreatment-Related TEAEs

Slide26

REALISETreatment-Related Epinephrine Use

Slide27

Long-Term Efficacy and Safety of EPIT (PEOPLE)

Study Design

Slide28

PEOPLEChanges in ED Over 3 Years

Slide29

PEOPLEChanges in Peanut IgG4 and IgE Levels

Slide30

PEOPLESafety Data

Slide31

Modeled Risk Reduction Through EPIT

Restaurant Meal Preparation

Slide32

Modeled Risk Reduction Through EPIT

Predicted Absolute Risk (AR)

Slide33

Modeled Risk Reduction Through EPIT

RRR at Month 12 DBPCFC

Slide34

Food Contamination in Restaurants

Talking to Patients and Parents

Slide35

Concluding Remarks

Slide36

Conclusions: Oral Immunotherapy

Slide37

Conclusions: Epicutaneous Immunotherapy

Slide38

Abbreviations

Slide39

Abbreviations (cont)