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Peanut Allergy Peanut Allergy Is an Unmet Medical Need Peanut Allergy Peanut Allergy Is an Unmet Medical Need

Peanut Allergy Peanut Allergy Is an Unmet Medical Need - PowerPoint Presentation

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Uploaded On 2022-02-12

Peanut Allergy Peanut Allergy Is an Unmet Medical Need - PPT Presentation

The Role of Skin as an Immune Organ The Skin Our First Line of Defense Immune Cells of the Epidermis The Skin as a Barrier Epidermis AllergenSpecific Immunotherapy Induces a TregMediated Immune Response ID: 908528

immunotherapy trial peanut phase trial immunotherapy phase peanut immune skin pepites results concluding mechanisms remarks design allergy palisade ar101

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Presentation Transcript

Slide1

Peanut Allergy

Slide2

Slide3

Peanut Allergy Is an Unmet Medical Need

Slide4

The Role of Skin as an Immune Organ

Slide5

The Skin: Our First Line of Defense

Slide6

Immune Cells of the Epidermis

Slide7

The Skin as a Barrier

Epidermis

Slide8

Allergen-Specific Immunotherapy Induces a Treg-Mediated Immune Response

Slide9

How Does EPIT Work?

Slide10

Induction of Tolerance

Slide11

Concluding Remarks

Slide12

Mechanisms of Risk Minimization for Peanut Exposure

Slide13

Desensitization

Slide14

Mechanisms of Immunotherapy

Slide15

Goals of Peanut Immunotherapy

Slide16

A Margin of Safety

Slide17

Concluding Remarks

Slide18

Strategies for Delivery of Allergen Immunotherapy

Slide19

AR101 PALISADE Phase 3 Trial

Design

Slide20

AR101 PALISADE Phase 3 Trial

Results

Slide21

PEPITES Phase 3 Trial

Design

Slide22

PEPITES Phase 3 Trial

Results

Slide23

Abbreviations