PPT-Drug-Receptor Interactions and

Pharmacodynamics DR Interactions and Pharmacodynamics Pharmacodynamics Describes the actions of drugs on the body and the influence of drug concentration on the magnitude of the response. . DR NARENDRA KUMAR. . Pharmacodynamics. is the study of the biochemical and physiological effects of drugs and their mechanisms of action. . Simply stated, . pharmacodynamics. refers to the effects of a drug on the body.. Pharmacodynamics. Pharmacodynamics. The study of the biochemical and physiologic effects of drugs and the molecular mechanisms by which those effects are produced . The study of what drugs do to the body and how they do it . Duri. . Xixi. Hong. . Joseph . Lustig. Aleksandra . Porebska. . C-. Src. Kinase Inhibition: . A Promising Route in Kidney Cancer Treatment. Outline. Overview of c-. Src. Activation/VEGF pathway. Jennifer N. Fosnot, Pharm.D.. Nurse Practitioners Symposium. Nashville, TN. September 27-28. th. , 2012. Objectives. 1.) Discuss the CYP 450 enzymes and common drug interactions with the immunosuppressants. Pharmacodynamics. Seyed. Ali . Ziai. Receptor. Pharmacologic antagonists. Macromolecular Nature of Drug Receptors. Regulatory proteins. Enzymes. Transport proteins . Structural proteins. . Receptor- Effector Coupling. Louis Wu, PA-C. Presented at VAPAA Annual Meeting. . March 2, 2017. . Financial Disclosures and Conflicts. I have no financial disclosures nor conflicts concerning this talk. . . Learning Objectives. Dr Shaheen. Delivered By . Dr Naser . Drug interactions- objectives. Discuss Pharmacokinetic interactions. List . Pharmacodynamic. interactions. Comment . on common Drug- Food interactions. Drug interactions. . Department . of Pharmaceutics. 1. 26-Feb-16. Drug interactions . :. . These are said . to occur when the pharmacological activity of a drug is altered by the concomitant use of another drug or by the presence of some other substance. . Drug-Drug Interactions. Basic mechanisms of drug-drug interactions. Clinical significance of drug-drug interactions. Minimizing adverse drug-drug interactions. Drug-Drug Interactions. Interactions can occur whenever a patient takes more than one drug.. An Antiretroviral Therapy Review. Sarah Pérez, PharmD, PhC, BCACP, AAHIVP. Disclosure. The speaker has no actual or potential conflicts of interest in relation to this presentation. . Objectives. Pharmacists. NUR 652. Mikael D. Jones, Pharm.D., BCPS. College of Nursing. College of Pharmacy. Introduction. Pharmacology. The study of drugs and their effects in and on the body. 3 Branches of Study in Pharmacology. Graded Dose-response Relationships. Agonist . drugs mimic the action of the original endogenous ligand for the receptor (for example, isoproterenol mimics norepinephrine on β1 . receptors . of the heart). The magnitude of the drug effect depends on the drug concentration at the receptor site, which, in turn, is determined by both the dose of drug administered and by the drug’s pharmacokinetic profile, such as rate of absorption, distribution, metabolism, and elimination. Opioid.   The class of drugs that includes opiates, . opiopeptins. , and all synthetic and . semisynthetic. drugs that mimic the actions of the opiates . Opioid. peptides.   Endogenous peptides that act on . Drug Drug Interaction Extraction from Product Labels . Bharath . Dandala. (. bdand@us.ibm.com. ). Diwakar Mahajan (. dmahaja@us.ibm.com. ). Ananya Poddar (. poddar@us.ibm.com. ). Introduction. Drug to drug interactions is the most common cause of adverse events, and preventable adverse events are the eighth leading cause of death in the United States..