PPT-A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular

Mark Loeb MD Professor McMaster University MLRGresearch Background Influenza increases the risk of CV events and deaths A lower rate of CV events related to ischemia and death has been reported with influenza vaccination. Randomiza tion if done properly can keep study groups as similar as possible at the outset so that the investigators can isolate and quantify the effect of the interventions they are studying No other study design gives us the power to balance unkno 1 What is live attenuated influenza vaccine LAIV 2 Why is LAIV an intranasal spray 3 Has LAIV been well studied 4 Why is LAIV not approved for use in Page 1 of 1. * required for saving. ^ conditionally required. *Facility ID:. DO NOT VACCINATE (Check one). (*Imprint patient information or place patient label here). Patient is less than 6 months old.. Vaccine Program. VRBPAC Meeting. . Robin Robinson, Ph.D. . Director, BARDA. Deputy Assistant Secretary, ASPR. February 29, 2012. 1. Pre-2003 Pandemic Influenza . Vaccine Goal & Strategy . Egg-based Vaccines. Vaccine Program. VRBPAC Meeting. . Robin Robinson, Ph.D. . Director, BARDA. Deputy Assistant Secretary, ASPR. November 14, 2012. U.S. Pandemic Influenza Plans Laid the Pathway for Pandemic Vaccines . Two funded influenza vaccines. Key campaign messages. 2018 promotional campaign . Eligibility. Influenza - the disease. 2018 vaccines and strains. Precautions and contraindications. Influenza and healthcare workers. placebo. REPORTING ADVERSE EVENTS AND COMPLETING THE REPORT FORM. Trial protocol code: ISRCTN30952488. Version 1, 17 November 2016. THIS PRESENTATION MUST BE USED WITH:. The Trial Protocol (. Section 2.9). ASCEND Randomized placebo-controlled trial of aspirin 100 mg daily in 15,480 patients with diabetes and no baseline cardiovascular disease Jane Armitage and Louise Bowman on behalf of the ASCEND Study Collaborative Why should I be concerned about influenza and pneumococcal disease? Pneumonia and influenza together are among the top 10 leading causes of death among Georgians over age 65. It is estimated that Michel Cucherat. Lyon. Liens d’intérêt en oncologie. BMS, MSD, Bayer, Novartis, . Gilead. Finalité pratique. Identifier si un essai thérapeutique démontre ou non l’intérêt clinique d’un nouveau traitement. Infarction. - a randomized, . double-blind, placebo-controlled, . multicenter . trial. 1. ClinicalTrials.gov . Identifier. : NCT02831608. Ole Fröbert, MD, PhD, FESC . - on behalf of the IAMI investigators. Q&As for health professionals Why did influenza policy change in 2013/14? his year, all healthy children aged two, three and four years, are being offered a vaccination against influenza. This follo RNA virus. of the family . Orthomyxoviridae. that is responsible for the infectious disease . influenza. (or most commonly referred to as flu) in birds, various mammals (such as pigs) and humans. Typically, influenza is characterized by fever, sore throat, chills and other non-specific symptoms, it is a much more severe disease. It is spread around the world in seasonal epidemics and according to World Health Organization, these annual epidemics result in about three to five million cases of severe illness, and about 250 000 to 500 000 deaths.. Investigator Kick-off Meeting. January 30-31, Clearwater, Florida. Jodie Riley, MISM and Robert Silbergleit. Adverse Events. Adverse Events (AEs) are “. . . any . untoward. medical occurrence in a subject that was not previously identified which does not necessarily have a causal relationship to the study drug…” .