PPT-Build-a-Genome Options for Genomes and Workflows

Lisa Scheifele Loyola University Maryland Timeline of synthetic genes and genomes Endy Science 3191196 The process of genome synthesis Edit and make changes Creation of synthetic life Assemble genome of . from Biological . Problem to . Combinatorial Algorithms. (and back). Pavel Pevzner. Department of Computer . Science,. . University . of California at San Diego. What is the evolutionary scenario for transforming one genome into the other?. Chapter 21. You must know. How prokaryotic genomes compare to eukaryotic genomes.. Applications of bioinformatics to medicine, evolution, and health.. The activity and role of transposable elements and retrotransposons in generating genetic diversity.. DNA. Double helix. Bases. Sequence. Gene . Key words. Genome . Genome sequencing. Species . Human Genome Project. DNA. is found in the nucleus of a cell. It is a long molecule that carries a set of codes to make you unique.. 6.1 Introduction to Genomics. 6.2 Sequencing Genomes. 6.3 Bioinformatics and Annotating Genomes. 6.1 Introduction to Genomics. Genome. Entire complement of genetic information. Includes genes, regulatory sequences, and noncoding DNA. Dr. Vladimir Teif. BS222 – Genome Science Lecture 1. Welcome to BS222 Genome Science!. Meet your lecturers. Vladimir Teif. (module supervisor). Leonard . Schalkwyk. Patrick . Varga-Weisz. Jordi . Paps. What you need to know:. The major goals of the Human Genome Project.. How . prokaryotic genomes compare to eukaryotic genomes. .. Applications of bioinformatics to medicine, evolution, and health.. The activity and role of transposable elements and . Ann . Lesnefsky. (Stanford University). Sarah Douglas (Harvard University). Julian . Damashek. (Stanford University). Bradley . Tolar. (University of Georgia). Hopkins Microbiology Course 2011. Comparative . Faculty of Science. Lagos State University. . Databases of Insect genomic resources: a review . Abdulazeez. Giwa. 1. *, . Oluwasegun. Gbenle. 2. and . Abiodun. . Denloye. 1. . . 1. Department of Zoology and Environmental Biology, Lagos State University, . Bas E. Dutilh. March 4. th. 2013. Protein function. Phenotypic. . function. E.g. . apoptosis. GO: . Biological. . process. Cellular. . function. E.g. . ribosome. GO: . Cellular. component. Molecular. Hardison. . Genomics 2_2. 1/7/15. 1. Y Chromosome. 3 billion bp = 3 Gb. Chr1 247 Mb. Chr12 132 Mb. Chr22 50 Mb. A human . genome (. male). The . genome. is . all the DNA. in a cell.. All the DNA on all the chromosomes. Circularly Permuted Genomes. Some phages have circularly permuted genomes. This means a linear concatamer of phage DNA is synthesized, used to fill a phage head, then cut when the head is full. Generally, one head will fit more than 100% of a genome, say, 103-110%. This ensures that wherever the DNA is cut, at least one working copy of each gene is present.. . The genome . of the infecting virus is replicated so that . viral transcription . can be amplified and to provide copies . of the . genome for progeny . virions. .. Generally, DNA viruses copy their genomes . “. User facility. providing high-throughput DNA sequencing & analysis in support of DOE missions in alternative . energy. , . carbon cycling . & . bioremediation. .”. Opened in 1999. ~240 UC Employees. Fahad Alqahtani and Ion Mandoiu. University of Connecticut. Computer Science and Engineering Department. Outline. Introduction & prior . w. ork. Our approach. Preliminary results. Conclusion and future work.