PPT-Immunotherapy in Multiple Myeloma: where do we go ?

Paul Moss Birmingham UK Outline Introduction to immunotherapy Immunotherapy in the setting of Myeloma Cellular therapy Future application History of Cancer Therapy Surgery 1000s of years Radiotherapy. What is smouldering myeloma? Smouldering myeloma (also known as asymptomatic myeloma) is a veryslow-growing type of myeloma. Myeloma, also known as multiple myeloma, is a type of bone marrow cancerari Ready for Prime Time?. DANA-FARBER . CANCER INSTITUTE. Nikhil C. Munshi, MD . Professor of Medicine . Harvard Medical School. Boston VA Healthcare System. Director . Basic and Correlative Sciences. Dana-Farber Cancer . Round Cell Tumors. Wendy Blount, DVM. Round Cell Tumors. Lymphoma. Mast Cell Tumor. Plasma Cell Tumor. Extramedullary Plasmacytoma. Multiple myeloma . Histiocytic Disease. Transmissible Venereal Tumor. NICE Guideline. Published Feb 2016. Adults with myeloma (and plasma cell leukaemia). Excluded:. Monoclonal . gammopathy. of uncertain significance (MGUS). Amyloidosis. Solitary . plasmacytomas. Included:. The Future of Cancer Care. Brad . Loncar. Biotech . commentator . and . investor for 8+ . years.. Manager of a biotech-focused family office.. Franklin Templeton Investments and U.S. Department of the Treasury.. Mike Chapman. University of Cambridge Department of Haematology. Novel agents have improved survival. What is a biomarker?. “A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention”. Smoldering Myeloma: To Treat or not to Treat Ruben Niesvizky MD Myeloma Center Myelomacenter.org run9001@med.cornell.edu CASE A 47-year-old man is diagnosed with smoldering multiple myeloma . He has Associate Professor Philip Beale. Chair ANZGOG Clinical Trials Group. Medical Oncologist Sydney. Concord Hospital. Chris O’Brien Lifehouse. Royal Prince Alfred Hospital. Outline. Background to immunotherapy. (Food Desensitization). Yale University ECHO Series. Session 5. Stephanie Leeds, MD FAAAAI. Disclosure. The following individuals have no conflicts of interest to disclose relevant to this activity:. Can we do better?. [Hospital name]. [Date]. What is myeloma?. Cancer of plasma cells. Leads to:. Bone infiltration. - fractures (especially vertebral wedge fractures), hypercalcaemia. - pain. Chemical Exchange Saturation Transfer (CEST) MRI . Sanhita Sinharay. (joining BSSE as an Assistant Professor in early 2021). https://faculty.mdanderson.org/profiles/sanhita_sinharay.html. Aggressive tumors are acidic. New treatments and new challenges. Laura Cove-Smith. Medical Oncology Consultant. The Christie NHS Foundation Trust. Manchester University NHS Foundation Trust . Session plan. Introduction to immunotherapy. H . Nèji. , H . Abid. , A . Mâalej. , S . Haddar. , R . Akrout. *, . M . Ezzeddine. *, S . Baklouti. *, . Z . Mnif. **, J . Mnif. Imaging department . Habib. . Bourguiba. Hospital, . *Rheumatology department . Grace B. Athas, Ph.D. . MLS. Department of pathology, LSUHSC. CLPC Spring seminar series, 2018 . Learning objectives. Review pathophysiology and lab diagnosis of plasma cell neoplasms with a focus on Multiple Myeloma.