PPT-Analysis of Next Generation Sequence Data

Author : luanne-stotts | Published Date : 2016-09-09

BIOST 2055 04062015 Last Lecture Genomewide association study has identified thousands of diseaseassociated loci Large consortium performs metaanalysis to further

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Analysis of Next Generation Sequence Data: Transcript


BIOST 2055 04062015 Last Lecture Genomewide association study has identified thousands of diseaseassociated loci Large consortium performs metaanalysis to further increase the sample size power to detect additional loci. Next Generation Sequencer Applications. DeNovo Sequencing. Resequencing, Comparative Genomics. Global SNP Analysis. Gene Expression Analysis. Methylation Studies. ChIP . Sequencing-transcription factors, histones, polymerases. Resource (. ViPR. ). :. an . Open Bioinformatics Database and Analysis Resource for Human Virus Pathogen . Research. Yun Zhang. 1. , Brett . Pickett. 1. , . Eva Rab. 1. , . Jyothi. . Noronha. 1. , R. Burke Squires. John Feo. Center for Adaptive Supercomputing Software. Pacific Northwest National Laboratory. October, . 2010. Graphs are everywhere in science. Astrophysics . Problem. : Outlier detection. . Challenges. 1 next - generation sequence data? An e xploration of unmapped DNA and RNA sequenc e reads from the bovine reference individual Lynsey K. Whitacre 1,2 , Polyana C. Tizioto 2, 3 , JaeWoo Kim 2 , Ta Brett . E. Pickett. 1. , Douglas S. Greer. 1. , Yun Zhang. 1. , . Liwei. Zhou. 2. , . Sanjeev. Kumar. 2. , Sam Zaremba. 2. , Chris Larsen. 3. , Edward B. Klem. 2. , Richard H. Scheuermann. 1. 1. J. Craig Venter Institute, San Diego, . Jenny . Wu. Outline. Goals : Practical guide to NGS data processing. Bioinformatics in NGS data analysis. Basics: terminology, data formats, general workflow etc.. Data Analysis Pipeline. Sequence QC and preprocessing. Jenny Wu. UCI Genomics High Throughput Facility. Outline. Goals : Practical guide to NGS data processing. Bioinformatics in NGS data analysis. Basics: terminology, data file formats, general workflow . Christopher Newport University. Carol Scovotti, D.P.S.. University of Wisconsin – Whitewater. Jacobs & Clevenger Case Writers’ Competition – . October . 3, 2015. Boston, Massachusetts. Here Come the Millennials!. S. cience. S. A. L. S. A. . HPC Group . http://. salsahpc.indiana.edu. School of Informatics and Computing. Indiana University. Bioinformatics Pipeline. Gene Sequences (N = 1 Million). Distance Matrix. Instructor: Vineet . Bafna. Today. We will explore the syllabus through a series of questions? . Please ASK. All logistical information will be given at the end. Introduction to the class. : Databases. Hierarchical genome shotgun HGS – Human Genome Project. “map first, sequence second. ”. clone-by-clone … cloning is performed twice (BAC, plasmid). Sequencing strategies. Whole genome shotgun WGS – Celera. Assistant Professor. Department of Medicine. Division of Pulmonary Sciences & Critical Care Medicine. What I do:. Perform high-throughput data analysis for . the scientific . community; microarray and . Analysis. Jessica Holmes. High Performance Biological Computing (HPCBio). Roy J. Carver Biotechnology Center. General Outline. Getting the RNA-Seq data: from RNA -> Sequence data. Experimental and practical considerations. Sequencing. . Paolo Aretini . Senior . Researcher. Fondazione Pisana per la Scienza. School on . Scientific. Data Analysis,. 25-28 . November. 2019. Scuola Normale Superiore . Outline. Introduction.

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