PPT-EXCRETION renal excretion, drugs affecting elimination of other drugs, blood concentration

I FACTORS AFFECTING DRUG ABSORPTION DISTRIBUTION plasmaprotein binding volume of distribution barriers blood brain and placental obesity and receptor combination METABOLISM oral medicines age nutrition and hormones. EXCRETION. HOW DO WE REMEMBER ALL THE LIFE PROCESSES?. H.N.T.R.S.G.E.R.M.R. WHICH ONES HAVE WE COVERED?. NUTRITION & TRANSPORT & RESPIRATION. WHAT’S NEXT ON THE LIST?. WHY ARE WE SKIPPING TO “E”?. Excretion of . Aristolochic. Acid I in . the IPK . Page . 1. Mariana Babayeva MD, PhD. Touro College of Pharmacy,. New York, NY, USA. Aristolochic. Acid I. Page . 2. Compound extracted from plant . Chapter . 2. Copyright © 2010 by John Wiley & Sons, Inc. All Rights Reserved. FORCES AFFECTING. GROWTH AND CHANGE. The changes that are occurring now in the business environment are tremendous. Managers must understand the various forces that are driving these changes and affecting their businesses in order to be effective. Nephron structure and function. Urine production . What is Excretion?. Excretion is the process by which metabolic waste and harmful substances are removed from the body. . These wastes are produced by chemical reactions occurring inside body cells (metabolism) . Structural Adaptations. of. Organisms. The break down of glucose to create ATP energy for cells. Occurs in the . mitochondria. Accomplished in various ways:. Ex.. Single-celled organisms(diffusion). Insects(spiracles & tracheal trunk). Chapter . 2. Copyright © 2010 by John Wiley & Sons, Inc. All Rights Reserved. FORCES AFFECTING. GROWTH AND CHANGE. The changes that are occurring now in the business environment are tremendous. Managers must understand the various forces that are driving these changes and affecting their businesses in order to be effective. DEPARTMENT . OF PHARMACEUTICS. . CONTENTS. . Renal clearance. . Hepatic clearance. . Organ clearance. . Total clearance. . Gut wall clearance . . Lung clearance. Metabolism. -is the sum total of all reactions going on in . cells.. Waste. -the reactions of metabolism produce a range of waste called excretory products, which the body needs to get rid of.. . The kidneys control acid-base balance by excreting either acidic or basic urine. Excreting acidic urine reduces the amount of acid in extracellular fluid. . E. xcreting basic urine removes base from the extracellular fluid. Acid and Base . Containing . Food:. 2. To . maintain health, . the diet should consist . of 60% alkaline . forming . foods and 40% acid . forming. foods. . To . restore health, the diet . should consist . 8). Department of Pharmacology and . Toxicology. . University of Al-. Mustansiriyah. 2018-2019. Absorption. :. Defined as the passage of a drug from its site of administration into the plasma. Therefore, it is important for all routes of administration, except intravenous injection. :. GLOMERULAR FUNCTIONS . : . About . 200 L of plasma . ultrafiltrate. usually enter the tubular lamina daily ,glomerular function measured as GFR ( glomerular . filtrarion. rate ) which is mean the volume of fluid filtered from the renal glomerular capillaries into . By . Dr.Qutaiba. . Abdulkareem. . Qasim. 2020. Topics to be discussed. 1-Renal function :. Renal glomerular function . Renal tubular function . Water reabsorption: urinary concentration and dilution . Ph.D. ). Department of Pharmacology and Therapeutics, . Afe. . Babalola. University,. Ado-. Ekiti. , . Ekiti. state.. Overview of renal functions. R. egulation . of water and electrolyte balances .