PPT-EXCRETION renal excretion, drugs affecting elimination of other drugs, blood concentration

I FACTORS AFFECTING DRUG ABSORPTION DISTRIBUTION plasmaprotein binding volume of distribution barriers blood brain and placental obesity and receptor combination METABOLISM oral medicines age nutrition and hormones. EXCRETION. HOW DO WE REMEMBER ALL THE LIFE PROCESSES?. H.N.T.R.S.G.E.R.M.R. WHICH ONES HAVE WE COVERED?. NUTRITION & TRANSPORT & RESPIRATION. WHAT’S NEXT ON THE LIST?. WHY ARE WE SKIPPING TO “E”?. Excretion of . Aristolochic. Acid I in . the IPK . Page . 1. Mariana Babayeva MD, PhD. Touro College of Pharmacy,. New York, NY, USA. Aristolochic. Acid I. Page . 2. Compound extracted from plant . Nephron structure and function. Urine production . What is Excretion?. Excretion is the process by which metabolic waste and harmful substances are removed from the body. . These wastes are produced by chemical reactions occurring inside body cells (metabolism) . DEPARTMENT . OF PHARMACEUTICS. . CONTENTS. . Renal clearance. . Hepatic clearance. . Organ clearance. . Total clearance. . Gut wall clearance . . Lung clearance. Metabolism. -is the sum total of all reactions going on in . cells.. Waste. -the reactions of metabolism produce a range of waste called excretory products, which the body needs to get rid of.. . Chapter 49. By: Kayla . Nida. This system is needed to allow for removal of impurities and waste from the body.. Helps maintain homeostasis in the body. Regulating Body temperature. Regulating Blood glucose. . PMR 04. Chapter 3: Excretion. Excretory organ. Concept of excretion. Test . A. B. C. D. E. F. G. H. I. A. B. C. Human excretory materials. water,. which is a product of cellular respiration and excess water absorbed from food in the large intestine.. Lectures. Drug Mechanisms. Receptor Interactions. Pharmacokinetics. Pharm definitions and drug selectivity. Drug= A chemical substance that interacts with a biological substance to produce a physiological effect. . Regulation of Drug Transport, Absorption, Distribution, Excretion and Metabolism. Dennis Paul, Ph.D.. Department of Pharmacology. 504-568-4740. rwainf@lsuhsc.edu. Principles of Pharmacology. Common processes and mechanisms whereby: . Pharmacokinetics of drugs . (ADME). . Are studies of . . A. bsorption. . D. istribution. . M. etabolism . . E. xcretion of drugs. Importance of PK studies. Patients may suffer:. Toxic drugs may accumulate. 8). Department of Pharmacology and . Toxicology. . University of Al-. Mustansiriyah. 2018-2019. Absorption. :. Defined as the passage of a drug from its site of administration into the plasma. Therefore, it is important for all routes of administration, except intravenous injection. Nature of Excretory products:. Ammonotelic. Uricotelic. Ureotelic. Nephron. . Formation of Urine. Filtration. Selective Re absorption. Tubular Secretion or Augmentation. Counter Current Mechanism . P’kinetics. Vd. . Shweta . yaragatti. Asst Professor Dept Of Dravyaguna. SMVVS RKM AMCH & RESEARCH CENTER . Email-. shwetayaragatti@gmail.com. Contents. Introduction. Pharmacokinetics. Absorption. diuresis. ). and sodium excretion (. natriuresis. ). RENAL TRANSPORT MECHANISMS . The kidney filters plasma water and solutes at the . glomerulus. at a very high rate (180 L/day) and must recover a significant percentage of most of these substances before excretion in the urine..