PPT-Gene Interaction and Epistasis

We know that many characteristics are passed on through genes Most of these characteristics are not passed on through one gene with only two alleles Most are polygenic where their traits are caused by a number of different genes. Some Questions. What would induce emigrants to leave everything behind and risk everything on moving elsewhere?. What considerations influence how individual human beings use space and act within it?. . GENE GENE INTERACTION. DOMINANCE. :-When one member of allellic pair marks the expression of the other member then it is known as dominance.. EPISTASIS. :-When there is suppression of action of a gene then it is known as epistasis.. Katie Wray. 25/06/2013. katie.wray@ncl.ac.uk. Drivers for Interaction. Why do we want more classroom interaction?. Do our students want classroom interaction?. Wealth of experience in the room. Getting a response / validation. . Dorret Boomsma. . Vrije Universiteit Amsterdam. Dept. Biological Psychology. No aspect of human behavior genetics has caused more confusion and generated more obscurantism than the analysis and interpretation of the various types of non-additivity and non-independence of gene and environmental action and interaction . 孙宝玺. . 北京工业大学. . . 合作者. : . 吕晓夫 四川大学. . . FHNP’15. The genotype/phenotype relationships explored by Mendel are valid but atypical. Most phenotypes are not derived from a single gene/single phenotype model.. Why?. More than two alleles often exist. Dominance of one allele over another may not be complete. Gene regulation Genetically related genotypes with striking phenotypic differences, but similar allelic architecture. Within a genotype – striking phenotypic differences between growth stages and/or between tissues. Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. Related organisms . Striking phenotypic differences but similar genetic structures . Within an organism . Phenotypic differences between growth stages and between tissues . The gene is there but not the expected . . Inter-locus Interactions. PBG 430. Locus. A. Allele A. Allele a. Locus. B. Allele B. Allele b. Phenotype. Inter-locus interactions . (Epistasis). Interaction(s) between alleles at different loci (i.e. interaction between genes). What do these two famous people have in common?. Title: . Using genetics. . . Thursday 23. rd. . January 2014. Homework: . Learning package 6 (apart from 1(c) ) for . Monday 27. th. January. Learning Outcomes. Steve Jupe. Motivation for Pathway and Network Analysis in Cancer. “. Exclusivity principle. ”. in cancer.. once a gene is mutated in a pathway, the selective growth advantage incurred by a second mutated gene in the same pathway is minimal.. Integrate molecular epidemiology approach to study potential mechanisms underlying diet-disease associations. jiantao.ma@tufts.edu. Contact info: . Example of Research Projects. Diet-gene interaction in relation to blood pressure change. Scenario: . General public encounter . (e.g., Wal-Mart) . Physical appreciation, eye contact is followed by flirting, small talk, and telephone number exchange. Figure out if he is looking for a relationship or just sex and look for red flags that he may be playing you.