PPT-Control of Eukaryotic Gene Transcription

Teachable Unit Gene Expression Team NANSI 2013 University of Minnesota Participants Michael Burns Lucy He David Kirkpatrick Bridget Lear Tamar Resnick Turk Rhen Facilitators Judy Ridgway Sue Wick. 7. 7 RNA Synthesis and Processing. Chapter Outline. Transcription in Prokaryotes. Eukaryotic RNA Polymerases and General Transcription Factors. Regulation of Transcription in Eukaryotes. RNA Processing and Turnover. to the beginning of a transcriptional cycle. Vladimir P. Zhdanov*. PHYSICAL REVIEW E 80, 051925 (2009). Outline. Preliminary. Introduction. Model . of Gene . Transcription. Experimental Results. Conclusion. Understanding:. Gene expression is regulated by proteins that bind to specific base sequences in DNA . The environment of a cell and of an organism has an impact on gene expression. Nucleosomes help to regulate transcription in eukaryotes. TSW – Recognize that the presence of a nucleus determines whether a cell is prokaryotic or eukaryotic. 6.12B. Cells. There are two . basic types . of cells. Prokaryotes. or prokaryotic cells . Eukaryotes. Topic 2.6 & 7.2. Understandings:. Transcription is the synthesis of mRNA copied from the DNA base sequences by RNA polymerase. . Gene expression is regulated by proteins that bind to specific base sequences in DNA.. Anablep. . anablep. . with its “4 eyes”. Upper half of lids look aerially while the lower half looks into the water.. Cells of the two parts of the eye exhibit differential gene expression. Individual bacteria respond to environmental change by regulating their gene expression. TUMOR SUPRESSOR PROTEINS. ATP. ENZYMES THAT CONTROL CELLULAR RESPIRATION. ADAPTIVE GENE PRODUCTS ARE ONLY REQUIRED UNDER CERTAIN CONDITIONS. GENES FOR PROTEIN DIGESTION ARE TURNED OFF WHEN THERE IS NO PROTEIN AVAILABLE. . 10.1 Between You and Eternity. Cancer is a multistep process in which cells grow and divide abnormally, disrupting physical and metabolic functions. More . than 200,000 new cases of breast cancer are diagnosed in the US each year – about 5,700 in women and men . Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. . 1. The . trp. Operon. Contains 5 genes coding for proteins (enzymes) required for the synthesis of the amino acid tryptophan. Also contains a promoter and operator.. When tryptophan levels in the cell are low, the expression of the . Controlling gene expression is often accomplished by controlling transcription initiation.. Regulatory proteins . bind to DNA to either block or stimulate transcription, depending on how they interact with RNA polymerase.. Central Dogma. The direction of the . flow of genetic information. is from DNA to RNA to polypeptide.. DNA Replication. Initiation and Unwinding of DNA. DNA . gyrase. . (. topoisomerase. ) unwinds the DNA coil.. . RNA. . transcription . &. Post transcription events. General differences between transcription and replication. Replication. Transcription. purpose. The purpose of replication is to conserve the entire genome for next generation.. Professional medical transcription services provided by SpectraScribe offer a streamlined solution for researchers seeking to extract meaningful insights from various research methodologies.