PPT-COX Inhibition and Blood Coagulation

By Jingtian Weng Cindy Nguyen Cassandra Lee Sarah BentoDe Sousa Presentation Date Sept 13 2016 PHM142 Fall 2016 Instructor Dr Jeffrey Henderson What is COX Two homodimer enzymes COX1 and COX2. Cox Conserves Overview Our Businesses Cox Enterprises is a leading communications, media and i i ih f l automot serv company i t revenues $15B and more than 60,000 employees. CoxEnterprisesCompani BY DR KAUKAB AZIM. 1. Learning Outcomes. By the end of the lecture the student should be able to . Define and discuss the pathobiology of pain pathways. Explain . the molecular mechanism of action common to all . Christian Jones, MD, MS, FACS. Johns Hopkins University School of Medicine. http://jonessurgery.com. . http://christianjones.md. . on-call@christianjones.md. . @. jonessurgery. Overview. M. odel and Its Extension with. . SPSS. . Jinheum. Kim (Univ. Suwon). 2015. 10. 17. Outline. The Cox PH model and its characteristics. Evaluating the PH assumption. The stratified Cox . model. Extension of . Acquired coagulation disorders:. They are . more common. than the inherited disorders. Unlike the inherited disorders, . multiple clotting. factor deficiencies are usual.. The acquired coagulation disorders.. Pratt & . Cornely. . Ch. 7. Enzyme Kinetics. How fast an enzyme catalyzed reaction goes. Why study enzyme kinetics?. Helps us understand mechanism of enzyme (how it works). Investigation of mutations in metabolic pathways. Pratt & . Cornely. . Ch. 7. Enzyme Kinetics. How fast an enzyme catalyzed reaction goes. Why study enzyme kinetics?. Helps us understand mechanism of enzyme (how it works). Investigation of mutations in metabolic pathways. Guy Young, MD. Children’s Hospital Los Angeles. University of Southern California Keck School of Medicine. Abbreviations. Abbreviations will be explained the first time the term appears on a slide. Created by Alyssa Black and Dominic Caputo. Edited by Margaret Hilton. Honors Organic Chemistry. Chem. 2321 (. Sigman. ), 2013. COX-2 Inhibitors and the COX-2 Active Site. Wiki Page: . COX-2 Inhibitors. A Strong Woman Who FEARS Her GOD, Mother, Sister, Friend, Entrepreneur, Restaurateur, Who Calls ALL The Shots & Won't Take No For An Answer. prostanoids. in the body.. These . prostanoids. including prostaglandins, prostacyclin and thromboxane . , they are . important biological mediators that play . important . role in the development of pain and inflammation in the body. So it is possible to get relief from pain and inflammation by inhibiting the COX enzyme.. in Pain. Overview – October 2015. Dmitry M. Arbuck, MD. President, Indiana Polyclinic. Clinical Associate Professor of Psychiatry and Pain Management, Marian University College of Osteopathic Medicine. Bruce Furie and Barbara C. Furie Center for Hemostasis and Thrombosis Research Division of Hematology/Oncology Departments of Medicine and Biochemistry New England Medical Center and Tufts University Dr. shatha Sami alyasrri. Assistant professor . Bleeding disorders during pregnancy and . delivery. . A. Inherited . Vascular abnormalities. Platelet disorders. Coagulation disorders. B.Acquired. Thrombocytopenia.