PPT-Liver

Ann Parasram 8 th February 2010 Liver Physiology What are LFTs Role of LFTs in investigation of Liver Disease Investigation of abnormal LFT Case studies Major functions of liver Carbohydrate Metabolism. Your Liver www.liverfoundation.org Functions of the liver . Synthesis . (. gluconeogenesis. , . glycogenesis. , protein, cholesterol, . coag. factors, bile) . Breakdown . (drugs and toxins, . glycogenolysis. , . bilirubin. metabolism, ammonia). Burden. Markedly decreased life expectancy. 12th leading cause of death in US. 25,000 deaths . annually in US. High morbidity and mortality due to complications. Cirrhosis. Alcoholic liver disease. Chronic hepatitis B. KNH 411. Pathophysiology of the Liver. Alcoholism. Chronic consumption of > 80 g of ethanol/day. Alcoholic liver disease (ALD). Dependency may be evident as tolerance or withdrawal. Ethanol rapidly and completely absorbed even with malabsorption. Lesson Overview. The liver . The gall bladder . Bile . The relationship with other intra-abdominal structures.. Liver. . The liver is a major organ in some animals, especially vertebrates (and therefore humans). It plays a major role in metabolism and has a number of functions in the body including-. Simon . Lynes. Definition. Progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. Aetiology. Vascular – Budd . Chiari. Infectious – viral hepatitis B and C. Kelsey Conrad. Annelise. . Chmelik. September 24, 2013. the . Liver. Largest organ in the body. Extremely complex organ. Filters harmful substances from the blood. Makes substances that digests food. Soheil Altafi MD. 1/27/15. DILI- Table of Contents. Introduction. Epidemiology. Liver - Drug Metabolism. Factors influencing Drug Metabolism. Mechanisms of Drug-induced Hepatotoxicity. Clinical Presentation. . LAYOUT. Definition. Epidemiology. Etiological classification. Clinical presentation. Approach to a child with CLD . Management. Upcoming research. . Chronic Liver Disease. . . Presence of ongoing injury within the liver. Starter: Histology of liver. What can you label?. Liver Lobules. Testing your Flip Learning. Learning Objective. Success Criteria. To know the structure of the liver. Describe with the aid of diagrams and photographs, the histology and gross structure of the liver. History . In 1963, Dr Baruch . Blumberg. accidentally discovered an antigen that detected the presence of hepatitis B in blood samples.. Dr . Blumberg. and his team identified a strange antigen from a blood sample of an Austrian Aborigine.. Due to liver damage and healing. Progresses through 4 stages, ending in cirrhosis. Liver cirrhosis causes more than . 1 million deaths per year. http://depts.washington.edu/hepstudy/definitions/uploads/49/Liver_Cirrhosis.png. Julia Gore Thornton MD, MPH. Staff Gastroenterologist. Summa Health Medical Center. Borderline and Mild Elevation of Liver Tests. American Journal of Gastroenterology Jan 2017. Formal review and literature search. Download PDF The Fatty Liver Solution™ eBook by Duncan Capicchiano - A natural and effective approach to tackling fatty liver disease.