PPT-Metabolic Changes of Drugs and Related Organic Compounds

Lecture 2 Oxidation of Olefins The metabolic oxidation of olefinic carboncarbon double bonds leads to the corresponding epoxide or oxirane Epoxides derived from olefins generally tend to be . organic compounds. isomers. functional groups . Much of the chemistry of life is based on organic compounds. organic compounds. have at least one carbon atom covalently bound to either:. another carbon atom. . and Cells. Elements of Life. A few major elements make up virtually all living things. Roughly 96% of an organism’s mass (including humans) is composed of just 4 elements. Oxygen. Carbon. Hydrogen. Another way of classifying chemical compounds… . Organic Compounds. In science, organic compounds contain . carbon. (. C. ), and usually . hydrogen. (. H. ). Sometimes other types of atoms are also attached, including: . Biochem. , Part 1. SOL Objective CH. 6. SOL CH. 6. Not really a separate objective. CH = chemistry, not chapter.. This year, we will have an Organic Chemistry and Biochemistry “flavor” from time to time.. Another way of classifying chemical compounds… . Organic Compounds. In science, organic compounds contain . carbon. (. C. ), and usually . hydrogen. (. H. ). Carbon has four electrons in its valence shell, which allows for more chemical bonding possibilities than any other element.. OXIDATION INVOLVING CARBON–NITROGEN SYSTEMS. Metabolism of nitrogen functionalities (e.g., amines, . amides) is . important because such functional groups are found . in many . natural products (e.g. Non living matter and minerals found on earth. The distinction between the organic and inorganic are not . a. bsolute ,but there is much overlap.. It has many applications in every aspect of pharmacy including catalysis in drug synthesis, pigments, surfactants and agriculture. Lémery. . nof. a chemistry book that classified substances according to their origin as mineral, vegetable, or animal. Compounds derived from plants and animals became known as . organic . and those derived from nonliving sources were inorganic.. Microorganisms such . as bacteria and fungi have been invaluable for discovering drugs and lead compounds. These microorganisms produce a large variety of antimicrobial agents which have evolved to give their hosts an advantage over their competitors in the microbiological world. Packet #1 (blue). (Buckle up, kiddoes!). Organic Chemistry. = The study of carbon-containing compounds. More specifically: those compounds that have a . carbon backbone. There are well over 1 million known organic compounds!. members. >10 . million. . organic. . compounds. !. How to . identify. . them. ?. . Molecular. formula. C. 4. H. 10. Extended. s. tructural. formula. Partially. . condensed. . structural. formula. Organic compounds must have carbon and hydrogen. Some examples of organic compounds includes carbohydrates, proteins and lipids. . Inorganic Compounds . Inorganic compounds have either one or none of carbon and hydrogen. Water is inorganic as it only has hydrogen and carbon dioxide is also inorganic. . Assitant. professor. Dr. D. Y. . Patil. ACSW College . Pimpri. , Pune - 18. Classification of bacteria. Bacteria . exhibit different modes of nutrition. They can be:- . Heterotrophic . bacteria . Autotrophic . (Nitri. t. e. . Tit. r. ation). Dr . Nisha. Sharma. INT. R. OD. C. TION. . The. . p. r. o. c. ess. . o. f. . f. or. m. i. n. g. . dia. z. onium. . c. o. m. p. oun. d. s. . o. r. . sa. l. ts.