PPT-Metabolic Changes of Drugs and Related Organic Compounds

Lecture 2 Oxidation of Olefins The metabolic oxidation of olefinic carboncarbon double bonds leads to the corresponding epoxide or oxirane Epoxides derived from olefins generally tend to be . Chhavi Agarwal, MD, FAAP, MRCP (UK). Assistant Professor. Division of Pediatric Endocrinology. Objectives. Metabolic Syndrome. Etiology. Relationship of various components . Primary care setting- Screening for the risk factors . organic compounds. isomers. functional groups . Much of the chemistry of life is based on organic compounds. organic compounds. have at least one carbon atom covalently bound to either:. another carbon atom. Dr. . Shatha. I . Alaqeel. 108 . Chem. Learning Objectives. Chapter five discusses the following topics and by the end of this chapter the students will:. . . Recognize the structure and classes of alkyl halides. Another way of classifying chemical compounds… . Organic Compounds. In science, organic compounds contain . carbon. (. C. ), and usually . hydrogen. (. H. ). Sometimes other types of atoms are also attached, including: . Biochem. , Part 1. SOL Objective CH. 6. SOL CH. 6. Not really a separate objective. CH = chemistry, not chapter.. This year, we will have an Organic Chemistry and Biochemistry “flavor” from time to time.. Another way of classifying chemical compounds… . Organic Compounds. In science, organic compounds contain . carbon. (. C. ), and usually . hydrogen. (. H. ). Carbon has four electrons in its valence shell, which allows for more chemical bonding possibilities than any other element.. Dr. . Nawal. . Makhseed. . MBBS, FAAP, FRCPC, DABMGG, FCCMG. Pediatric Metabolic Consultant. Second . Jahra. Pediatric conference 5-6 May/2017 . What is a metabolic disease?. Small molecule disease. The study of compounds made only by living cells. The study of carbon compounds. The study of vital forces. The study of natural compounds . (as opposed to synthetic or man-made). The study of hydrocarbons. Normal fasting range . of blood glucose . = 60–100 . mg/. dL. . (3.3–5.6 . mmol. /L). In general, . neurohormonal. control of glucose production in . healthy individuals . maintains a fasting serum glucose . OXIDATION INVOLVING CARBON–NITROGEN SYSTEMS. Metabolism of nitrogen functionalities (e.g., amines, . amides) is . important because such functional groups are found . in many . natural products (e.g. Bayu. Lestari. What will be Impaired in This Patient?. Obese. Insulin Resistance?. Dyslipidemia? (High TG, High LDL, Low LDL). T2DM?. Metabolic Syndrome. High prevalence of metabolic . s. yndrome: relation between glucose and lipid metabolism. Lémery. . nof. a chemistry book that classified substances according to their origin as mineral, vegetable, or animal. Compounds derived from plants and animals became known as . organic . and those derived from nonliving sources were inorganic.. Microorganisms such . as bacteria and fungi have been invaluable for discovering drugs and lead compounds. These microorganisms produce a large variety of antimicrobial agents which have evolved to give their hosts an advantage over their competitors in the microbiological world. Organic compounds must have carbon and hydrogen. Some examples of organic compounds includes carbohydrates, proteins and lipids. . Inorganic Compounds . Inorganic compounds have either one or none of carbon and hydrogen. Water is inorganic as it only has hydrogen and carbon dioxide is also inorganic. .