PPT-Epigenetics and DNase- Seq

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BMICS 776 wwwbiostatwiscedubmi776 Spring 2018 Anthony Gitter gitterbiostatwiscedu These slides excluding thirdparty material are licensed under CC BYNC 40 by

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Epigenetics and DNase- Seq: Transcript

BMICS 776 wwwbiostatwiscedubmi776 Spring 2018 Anthony Gitter gitterbiostatwiscedu These slides excluding thirdparty material are licensed under CC BYNC 40 by Anthony Gitter Mark Craven and Colin Dewey. The indicated amount of rDNase I was added to 50 57346L of 1X DNase I Buff er The sample in lane 3 was treated with 5 57346L of DNase Inactivation Reagent Next genomic Lambda DNA 1 57346g was added to each tube and incubated for 10 min at 3757520C t Kevin Ferriter. Mariah Minder. From Yesterday…. Do you think your brain cell and your blood cell have the same DNA sequence?. Genetics. Every cell contains all of your DNA. Not every cell expresses all of your DNA. :. DNA . methylation. II. DNA . methylation. in plants (Ch9). Differences between plants and animals. Auxotroph . vs. . heterotroph. Sessile . vs. . mobile. Motionless and rigid . vs. . migrating and flexible cells. -What is epigenetics? -Epigenetics and us -Past, present, and future You Are What Your Mother Ate:What is Epigenetics?Daniel Lieber DNA is the Source of Heritable Information in the Cell organism Crea Daniel Messinger. , Ph.D.. Messinger. Hmmm…. ‘Mothers . who were . pregnant during a 1944 famine in the . Netherlands. were . more likely to have children—and grandchildren—prone to heart disease, diabetes, and obesity. . . Samudra. K. . Wijeratne. , Ph.D.. Dept. of Nutrition and Health Sciences, UNL. Processes in . Epigenetics. The . study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA . How do we make this work?. Dr. Paul S. Anderson. NYANP. 2017. (c) PS Anderson - www.ConsultDrA.com - 2017. 1. Dr. Anderson - Disclosures. Ownership interest in:. • Advanced Medical Therapies Clinic Seattle, WA. Joo. ’ Kim. Louisiana State University. What is . Epigenetics. ?. “the study of mitotically and/or . meiotically. heritable changes in gene function that can not be explained . by changes . in DNA sequences” – (Riggs et al. 1996). http://www.knowabouthealth.com/wp-content/uploads/2010/06/mcdonalds_.jpg. http://emilyscarenhealth.wordpress.com/2011/10/04/attention-a-must-read-for-smokers/. Can “. nuture. ” change “nature” ?. Zhiping Weng. U. Mass. Medical School. Simons Institute, UC Berkeley, March 10, 2016. 1. The . Enc. yclopedia . O. f . D. NA . E. lements Consortium. Goals:. Catalog all functional elements in the genome. Epigenetics comprises (hereditary) changes in gene expression without altering the DNA sequence . Epigenetics is a biological subdiscipline that deals with questions of development, heredity, gene regulation and evolution . JABLONKA & LAMB: CHANGING CONCEPT OF EPIGENETICSment. We will then consider the practical importance of epigenetics in med-icine, agriculture, and ecology and, finally, look at the implications thatre BMI/CS 776 . www.biostat.wisc.edu/bmi776/. Spring 2019. Colin Dewey. colin.dewey@wisc.edu. These slides, excluding third-party material, are licensed under . CC BY-NC 4.0. by Anthony Gitter, Mark Craven, and Colin Dewey. ‘Epi’: On top of. . Definition:. The . study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.. DNA. How many cell types are in the human body?.

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