PPT-Differential Expression of SOCS1/SOCS3 Ratios in Virus-Infe

Nancy J Bigley PhD Microbiology and Immunology Program and Department of Neuroscience Cell Biology and Physiology College of Science and Mathematics and Boonshoft School of Medicine Wright State University Dayton Ohio . limma. package. 20 March 2012. Functional Genomics. Linear regression. Fit a straight line through a set of points such that the distance from the points to the line is minimized. The slope of the line is adjusted to minimize the . Ju. . Han Kim . Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea, . Presenter: Zhen Gao . 2. Outline. Review of major computational . approaches to facilitate biological interpretation of . Introduction to Systems Biology Course. Chris . Plaisier. Institute for Systems Biology. Glioma. : . A Deadly Brain Cancer. Wikimedia commons. miRNAs in Cancer. Caldas et al., 2005. RISC. Utility of miRNAs in Cancer. Guiming. Wang, Richard B. . Minnis. , Jerrold L. . Belant. , & Charles L. Wax. What is West Nile virus?. WNV is a disease transmitted by mosquitoes.. Symptoms range from mild to severe and include:. Rongtuan Lin . Lady Davis Institute for Medical Research. Department of Medicine. McGill University, . Montreal, . CANADA. Vaccines-2014. Valencia, Spain. September 24, 2014. Retinoic acid-inducible gene-I (RIG-I)-like receptors (. Nancy J. Bigley. , Ph.D.. Microbiology and Immunology Program, and Department of Neuroscience, Cell Biology, and Physiology ,College of Science and Mathematics and . Boonshoft. School of Medicine, Wright State University, Dayton, Ohio . Prokaryotes and eukaryotes precisely regulate gene expression in response to environmental conditions. In multicellular eukaryotes, gene expression regulates development and is responsible for differences in cell types. Nancy J. Bigley. , Ph.D.. Microbiology and Immunology Program, and Department of Neuroscience, Cell Biology, and Physiology ,College of Science and Mathematics and . Boonshoft. School of Medicine, Wright State University, Dayton, Ohio . analysis - outliers. V2: batch effects. V3: data imputation. What . is measured by microarrays?. Microarray normalization. Differential gene expression (DE) analysis based on microarray data. Detection of outliers. Reperant LA, van Amerongen G, van de Bildt MW, Rimmelzwaan GF, Dobson AP, Osterhaus A, et al. Highly Pathogenic Avian Influenza Virus (H5N1) Infection in Red Foxes Fed Infected Bird Carcasses. Emerg Infect Dis. 2008;14(12):1835-1841. https://doi.org/10.3201/eid1412.080470. Goncé A, Martínez MJ, Marbán-Castro E, Saco A, Soler A, Alvarez-Mora M, et al. Spontaneous Abortion Associated with Zika Virus Infection and Persistent Viremia. Emerg Infect Dis. 2018;24(5):933-935. https://doi.org/10.3201/eid2405.171479. What is measured by microarrays?. Microarray normalization. Differential gene expression (DE) analysis based on microarray data. Detection of outliers. RNAseq. data. DE analysis based on . RNAseq. data. RNA-Seq. G-OnRamp Beta Users Workshop. Wilson Leung. 07/2017. Outline. Design considerations for RNA-Seq experiments. Interpret FastQC results. Optimize alignment parameters for HISAT. Assess alignment statistics with CollectRnaSeqMetrics. Bozza FA, Moreira-Soto A, Rockstroh A, Fischer C, Nascimento AD, Calheiros AS, et al. Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil. Emerg Infect Dis. 2019;25(2):311-315. https://doi.org/10.3201/eid2502.180166.