PPT-Visceral Leishmaniasis treatment access: The reality on the ground

Margriet den Boer KalaCORE Regional Coordinator East Africa Symposium Innovation for Access to Treatment for Neglected Diseases ASTMH February 9 Nairobi 2015 photo by K alaCORE 2015 photo by . presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . Leishmaniasis.  . By. Tarik. . Zaher. ,MD. Assistant Professor of Endemic and Tropical Medicine ,. Zagazig. University. Background. Leishmaniasis. is a . protozoal. disease capable of causing a spectrum of clinical syndromes ranging from . – . Experiences In . Marsabit. County. Presented by: . Abduba. . L. iban. . CDSC, . Marsabit. County. 0n 9. th. February 2016 at the ASTMH Conference. outline. Brief county profile. S. tatus of . Margriet. . den . Boer. KalaCORE Regional Coordinator , East Africa. Symposium Innovation for Access to Treatment for Neglected Diseases. ASTMH, February 9, Nairobi. 2015, photo by . K. alaCORE. 2015, photo by . presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . – . Experiences In . Marsabit. County. Presented by: . Abduba. . L. iban. . CDSC, . Marsabit. County. 0n 9. th. February 2016 at the ASTMH Conference. outline. Brief county profile. S. tatus of . Tel.: +91-0612-2221797, Fax:+91-0612-2239423 “History of kala-azar is older than the dated • Leishmaniasis• Internal leishmaniasis• Visceral • General • Kala-azar of
:   . Sarcomastigophora. 2 medically important genera: . Trypanosoma. and . Leishmania. Important pathogens of . humans. All pathogenic species transmitted by . insects. All have more or less complex cycles alternating from one morphologic form to another. . Suhad Faisal . Hatem. . Flagellate of blood and tissue . This parasite include two genus . Leishmania. spp. . . and. . Trypansoma. spp. .. They are pathogenic to man and may exist in two or more form in life cycle (. The promastigote stage (long, slender form with a free flagellum) is present in the saliva of infected sandflies. Human infection is initiated by the bite of an infected sandfly, which injects the promastigotes into the skin, where they lose their . Clinical Phenotypes. Cutaneous . Leishamaniasis. Mucocutaneous. . Leishmaniasis. Visceral . Leishmaniasis. Post Kala-azar dermal . leishmaniasis. Phenotypes . o. f the . Leishmaniases. VISCERAL LEISHMANIASIS. Addis. . Ababa. . University. WorldLeish6 . Congress. , . Toledo, Spain. LEAP: . Contributing. to . Strengthening. . Clinical. Trial . Capacity. , . Treatment. and Control of VL in . Eastern. Africa . Bhattarai NR, Van der Auwera G, Rijal S, Picado A, Speybroeck N, Khanal B, et al. Domestic Animals and Epidemiology of Visceral Leishmaniasis, Nepal. Emerg Infect Dis. 2010;16(2):231-237. https://doi.org/10.3201/eid1602.090623.