PPT-Diuretics Victor Nadler Objectives

By the end of this class students will be able to Describe the mechanisms of renal ion and water reabsorption that are most relevant to diuretic action Name the major diuretics used in clinical medicine. Brogan Spencer and Laura . Smitherman. What is a diuretic? . Substance . that promotes the formation (excretion) of urine. Name 3 common and important diuretics. Loop diuretics. Thiazide diuretics. Potassium sparing diuretics (action at . furosmide. Made by . Zainab. . Albar. Supervised by . Dr.Ahmad. Shaker. Types of diuretics. Loop diuretics . ( furosemide , . Bumetanide. , . Torasemide. and . Ethacrynic. acid ).. Thiazide. . A. Kidney functions. Kidneys have a number of essential functions:. 1. excretion. 2. regulate: . fluid balance . electrolyte composition . acid-base balance . 3. secrete enzyme renin . . 4. secrete erythropoietin (a hormone that stimulates RBC. and Diet. Vivek Bhalla, MD. Division of Nephrology. Stanford University School of Medicine. September . 14th, 2015. Anatomy of the Renal Block. Physiology. Pathophysiology. Urology. Body. Fluids -1. Dr. Pran Kishore Deb & Dr. . Bilal Al-. jaidi. Assistant Professor, Pharmaceutical Medicinal Chemistry. Faculty of Pharmacy, Philadelphia University-Jordan. Email: . pdeb@Philadelphia.edu.jo. . Diuretics. Most . diuretics also increase urinary excretion of solutes, especially sodium and . chloride. Most . diuretics that are used clinically act by decreasing the rate of sodium reabsorption from the . tubules . . Care and Handling of Medications and Solutions. Medication Identification:. Medications come in a variety of packaging. Glass, Metal, and Plastic. Common Types of Containers in the OR:. Ampule Tubes . 8. NOTES. BY MARY. . SHELLEY. The Individual. The Romantics had a preoccupation with the genius, the hero, and the exceptional figure. They focused on his passions and inner struggles. They viewed the artist as a supremely individual creator, whose creative spirit is more important than strict adherence to formal rules and traditional procedures . Sommaire :. Introduction. Enfance & débuts littéraires. Carrière. Le Romantisme. Fin de sa vie. Enfance :. ⇒ V. Hugo né en 1802 à Besançon. Benjamin d’une famille de 3 enfants.. => Fils du général Joseph Léopold Sigisbert Hugo (général et aristocrate) et de Sophie Trébuchet (bourgeoise nantaise). . Background. Primary effect of diuretics is to increase solute excretion, mainly as NaCl. Certain disease states may cause blood volume to increase outside of narrowly defined limits. Hypertension. Congestive heart failure. . Alwali. Assistant Professor in Pharmacology. College of Pharmacy-Al-. Nahrain. University. 1/3/2018. 1. Diuretics. are drugs that . increase the volume of urine excreted. . . Most diuretic . agents are . . Most diuretic agents are inhibitors of renal ion transporters that decrease the . reabsorption. of Na+ at different sites in the . nephron. . . As a result, Na+ and other ions, such as . Cl. −, enter the urine in greater than normal amounts along with water, which is carried passively to maintain osmotic equilibrium.. diuresis. ). and sodium excretion (. natriuresis. ). RENAL TRANSPORT MECHANISMS . The kidney filters plasma water and solutes at the . glomerulus. at a very high rate (180 L/day) and must recover a significant percentage of most of these substances before excretion in the urine.. HEART FAILURE, ANTIARRHYTHMICS . Ischaemic. . Heart. . Disease. . Cardiomyopathy. Arterial. . hypertension. Severe . dysrrhytmias. myocarditis. Acute. . Coronary. . Syndroma. (AIM…). . pulmonary.