PPT-Important or Imposter? HDL - Cholesterol

The wider roles of HDL HDL and Reverse Cholesterol Transport Phospholipid Glycosphingolipid Cholesterol Lipid Raft Normal Cell Membrane Membrane rafts are small 10200 nm heterogeneous cholesterol amp . d. e. . determina. t. ion. Int. r. oduct. i. on:. T. r. i. gly. c. e. r. i. d. es. . a. r. e. . es. t. e. r. s. . of fatty. . ac. i. ds. . and. . a. r. e. . hydro. l. yzed. . to. . gly. c. e. Rachel . Randle. Clinical Scientist in-service HSST. Viapath Bedford Hospital. Dr W Wassif. Consultant . Chemical . Pathologist. Bedford Hospital. On behalf of National . Clinical Biochemistry Audit Group. Cholesterol is an essential lipid constituent of cell membranes. Cholesterol is a precursor of steroid hormones and of bile acids. Intermediates of cholesterol biosynthesis are required to make vitamin D and for posttranslational modification of membrane proteins. Arterio. sclerosis. Thickening/Hardening of Arteries. Predominantly . Athero. sclerosis. Normal vessel structure. Pathophysiology of Brain & Body . USSJJQ-20-3. Normal Structure. Normal Structure. Assist.Lecturer. Aseel. . Ghassan. . Daoud. M.Sc. in Pharmacy/Clinical Laboratory Sciences. What is HDL?. It is a high density lipoprotein, which is one of the classes of lipoproteins that carry cholesterol in the blood.. Plasma lipids . 200 . Lipoproteins . 201 . Fatty acids . 200 . Disorders of lipid metabolism . 207 . Cholesterol . 201 . Investigation of hyperlipidaemias . 214 . FATTY ACIDS . Lipids play a critical role in almost all aspects of . ????????????????? ? Cholesterol is a fatty substance, vital for good health. It helps form cell membranes, various hormones, bile and vitamin D. We get some cholesterol from our diet but most is made This is a thick, hard deposit that can narrow the arteries and make them less flexible. This condition is known as atherosclerosis. As the artery narrows and hardens, less blood can get through causin Chole lipoproteins, which got their name because they’re made of fat (lipid) and proteins. The two types of lipoproteins that carry cholesterol to and from c ells are low - density lipoprotein, or into cardiovascular protection []. Furthermore, as some glucose-lowering medications have shown to increase the risk for major adverse cardiovascular events (MACE), regulatory agencies require that al Toll Free: 800-445-9853 Fax: 734-483-1592 www.pointescientific.com For the quantitative determination of High Density Lipoprotein (HDL) in Cholesterol in serum. Early methods of H steviol. , on high density lipoprotein biogenesis. Aimee Furlan. 1,2. , . Xiaohu. Mei. 2. , Haya Herscovitz. 2. Design Tech High School, 275 Oracle Pkwy, Redwood City, CA 94065. 1. ; . Department of Physiology and Biophysics, Boston University, 700 Albany St, Boston, MA 02118. , MD, FRCPC, FACP, CCD, ECNU.. Asst. Professor and Consultant . Medicine, Endocrinology. Department of Medicine, King Saud University. Lipid Transport. LPL/Apo C2. Rader DJ, Daugherty, A Nature 2008; 451:904-913 . They bind with . soluble . protein. complexes . called. . lipoproteins. Lipids . can . be derived from food (exogenous) or synthesized. in the body (endogenous). The water-soluble (polar). groups of proteins, phospholipids and free cholesterol.