PPT-Amino Acids

C483 Spring 2013 Questions 1 Amino acids with non ionizable side chains are zwitterions when they are A in any solution D in alkaline solutions only B at physiological pH pH 74 . (Foundation Block). Dr. Ahmed Mujamammi. Dr. . Sumbul. . Fatma. Learning outcomes. What are the amino acids?. General structure.. Classification of amino acids.. Optical properties.. Amino acid configuration.. CHAPTER 3, Part 1 . Amino Acids and Peptides . To know the structure and naming of all 20 protein amino acids. To know the structure and properties of peptides and the particularly the structure of the peptide bond.. Debalina. . Mukhopadhyay. . . Containing carbon, hydrogen, nitrogen, oxygen. . Building blocks of protein. . Contain Amino group (NH2+) , carboxyl . group . (COO-) , Alkyl group (R ) / H . . alpha carbon contains the functional groups.. (Foundation Block). Learning outcomes. What are the amino acids?. General structure.. Classification of amino acids.. Optical properties.. Amino acid configuration.. Non-standard amino acids.. Derivatives of amino acids.. Subunits (building blocks) of peptides and proteins. Neurotransmitters. Metabolic intermediates. glutamate. γ. -. aminobutyric. acid. (GABA). Proteins are synthesized from 20 ‘standard’ . α. -amino acids. Their names have 3- and 1-letter abbreviations.. DR AMINA . BIOCHEMISTRY. All tissues have some capability for synthesis of:. The non-essential amino acids,. Amino acid remodeling, . and Conversion of non-amino acid carbon skeletons into amino acids and other derivatives that contain nitrogen. . amine group. Draw. a carboxylic acid group. Join. them together to form a molecule with an amine and . a carboxylic acid . group. Amino Acids. Building blocks of proteins. Two functional groups: a carboxylic acid and a primary amine. Part 1 - Amino Acids. Structure and Chemistry. Building Blocks of Proteins. Essential Amino Acids. Basic Structure. Stereochemistry. Side Chain Chemistry. Properties. Ionization. Bonding. Amino Acids & Proteins. Proteins. TextBook. : . HARPERS . REVIEW OF BIOCHEMISTRY. Anatomy of an amino acid. . -Amino acids. A. Example. (glycine). 2-aminoethanic acid. (alanine). 2-aminopropanoic acid. (aspartic acid). 2-aminobutane-1,4-dioic acid. Amino Acids. Amino acid play A central role as building block of proteins.. Amino acids also converted to specialized products.. More than 300 different amino acids have been described in nature, only 20 are commonly found in mammalian proteins... . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . backbone.  . atoms . (see aminoAcids1).  but a unique set of . side chain . atoms. It's the side chains that make the 20 amino acids different from each other. . 1. Use the three identical backbone pieces and three unique side chain pieces below to construct three amino acids in the space to the right.. imino. acid.” . Figure 5: Comparison of the secondary amino group found in proline with the primary amino group found in other amino acids such as alanine.. 2. Proline: . Proline differs from other amino acids in that its side chain and amino N form a rigid, five -member red ring structure (Figure 5). Proline, then, has a secondary (rather than a primary) amino group. It is frequently referred to as an “. BSc 3. rd. year . AMINO ACIDS. C. lassification of amino acids . Classification according to nature of side chain. PREPARATION OF AMINO ACIDS. 1. Gabriel Phthalimide synthesis. 2. Strecker’s synthesis.