PPT-Immunological Disorders

Introduction A There are three types of immunological disorders 1 Hypersensitivity 2 Autoimmune disease 3 Immunodeficiency B Hypersensitivity reactions to usually harmless substances are often called allergies or allergic reactions. Chris Lancaster, Emily Mathews, Jake Turner . Questions:. c.j.lancaster@warwick.ac.uk . Jake.Turner@warwick.ac.uk. E.K.Mathews@warwick.ac.uk. Definitions . Immunological . Tolerance:. Unresponsiveness . in newborns Nirupma Trehanpati * , Syed Hissar * , Shikha Shrivastav * & Shiv K. Sarin *,** * Departments of Research & ** Hepatology, Institute of Liver & Biliary Sciences, New Delhi, India Receive Sheena Wheeler. Dr. Anna . Jolles. Many . human diseases are transmitted from non-human animals (. Zoonotic. diseases). Some species are better at transmitting diseases than others. Biodiversity is important . . Immunology. Prof. MUDr. Zdenka . Ulcova. -Gallova, DrSc.. Genetics. –. Pilsen. and Department . of. . Gynecology. and . Obstetrics. . of. Charles University, . Pilsen. , Czech Republic. www.ulcovagallova.cz. immune regulation -- 1. Abul K. . Abbas. UCSF. FOCiS. 2. Lecture outline. Principles of immune regulation . Self-tolerance; mechanisms of central and peripheral . tolerance. Inhibitory receptors of T cells . 58% Adults Snore. 36% Complain of Insomnia. 15% note persistent Excessive Daytime Sleepiness. 3% Unusual Nocturnal Behaviors. 28% Workforce on night or rotating shifts. One in Three Individuals are Dissatisfied with Their Sleep. Definition. Normal anxiety. Anxiety symptom. Anxiety disorders. generalized anxiety disorder. panic disorder . phobias. obsessive compulsive disorder. acute stress and post traumatic stress disorders. Immune Responses. Applications of the Immune Response. A. Vaccination – the practice of deliberately stimulating the immune system in order to protect individuals against a disease. 1. Edward Jenner developed the first official smallpox . Polydactyly. Down Syndrome. Hemophelia. Progeria. Hypertrichosis. Sickle Cell Anaemia. INTRODUCTION. What is genetic diseases/disorders?. The human body is composed up of cells , each one specializing a particular function like sensing light, smelling . By: . Dr Puneet Kumar Gupta . Assistant Professor, Microbiology. 1. 2. 3. 4. 5. 6. 7. 8. Tolerance and Autoimmunity. 9. What is tolerance?. Mechanisms to protect from potentially self reacting lymphocytes. . DSM-IV lists 10 separate personality disorders, with an average prevalence of 1-2%. Three clusters: anxious-fearful, odd-eccentric, and dramatic-impulsive. Concern:. . Categorical vs. Dimensional (DSM-V)?. . immunological tolerance. Immunological . tolerance is a state of unresponsiveness to a particular antigen to which a person has been exposed earlier. .. . . The important aspect of tolerance is the self-tolerance, which prevents the body to mount immune response against self-antigens. Immunological unresponsiveness to self is referred to as . tolerance. or . self-tolerance. Very important to human health. How is this achieved?. -cells with receptors for self-antigens are destroyed in the thymus or bone marrow (central tolerance). From Division of Allergy/Immunology/Rheumatology, Department of Pediatrics, Faculty of Medicine, Ramathibodi E-mail: Suwat.ben@mahidol.ac.th Submitted date: 29/10/2012 Accepted date: 12/6/2013 Abbre