PPT-Basic Local Alignment Search Tool

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Altschul etal 1990 傅安陳岳昇陳宗涵 20161212 Outline Introduction and Methods Results Conclusion Introduction Measures of similarity between sequences

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Basic Local Alignment Search Tool: Transcript

Altschul etal 1990 傅安陳岳昇陳宗涵 20161212 Outline Introduction and Methods Results Conclusion Introduction Measures of similarity between sequences to distinguish biologically significant relationships. Basic Local Alignment Search Tool Stephen F Altschul Warren Gish Webb Miller2 Eugene W Myers3 and David J Lipmanl Satwnal Center for Biotechnology Informalion Kdional Library of Medicine National Insti Image from http://graphics.cs.cmu.edu/courses/15-463/2010_fall/. A look into the past. http://blog.flickr.net/en/2010/01/27/a-look-into-the-past/. A look into the past. Leningrad during the blockade. CS/. BioE. 598. Tandy Warnow. Alignment Error/Accuracy. SP-FN: percentage of homologies in the true alignment that are *not* recovered. SP-FP: percentage of homologies in the estimated alignment that are false. Scott Walmsley, PhD. Research Instructor, Department Pharmaceutical Sciences. Skaggs School of Pharmacy. Outline . What is and why perform Multiple . S. equence . A. lignment (MSA)?. Pre-requisite knowledge. output. How to . measure. the similarity between two sequences. Q: which one is a better match to the query ?. Query: . M. . A T. . W . L. . . Seq_A: . M. . A T. P P . Seq_B: . M. P P . W . A. Adriansyah. 1. ,. J. Munoz Gamma. 2. , . J. Carmona. 2. , B.F. van Dongen. 1. , . W.M.P. van der Aalst. 1. Tallinn, 3 September 2012. Department . of Mathematics and Computer Science, Eindhoven University of . Kiyomi. . Seiya. . Aperture scan. . B75 : Aperture scan program with new corrector. . Kent Triplet, Alex Waller. . BPM data from B40 to B:HPXXX, B:VPXXX. . Sharon Lackey. . Data taking and offline analysis. and . pairwise. alignments. 1. “. It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead of theories to suit facts.. ” . (. A. Conan Doyle, . Xuhua Xia. xxia@uottawa.ca. http://dambe.bio.uottawa.ca. Xuhua Xia. Slide . 2. Normal and Thalassemia HBb. Are the two genes homologous?. What evolutionary change can you infer from the alignment? . What is the consequence of the evolutionary change?. Choose a Vehicle you are comfortable with.. Be Consistent and always use same Vehicle’s.. Retain Control of Demonstration. ORDER OF PRESENTATION. Show Estimator (Only if not Showing Teamworks). Show Quotes and Shop Set-up (. Below are some key features of the Basic Dictionary.. Search in any of 30 Languages. Search by Definition. Search by Sound. Search by Qualitative criteria such as Good/Bad and Less/More. Display Interactive Graphs of Word Relationships. Jia. -Ming Chang, Paolo Di . Tommaso. , and Cedric . Notredame. TCS. : A new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree . reconstruction, . Você gosta de emagrecer? Ou de perder 5kg ou 10kg? Independentemente da sua resposta, esse
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Eudeslima08@gmail.com Outline I ntroduction BLAST s earch s teps Step 1: Specifying Sequence of interest Step 2: Selecting BLAST Program Step 3: Selecting a Database Step 4: Selecting Search Parameters and Format

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