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 Updates in Diffuse Large B-Cell Lymphoma  Updates in Diffuse Large B-Cell Lymphoma

Updates in Diffuse Large B-Cell Lymphoma - PowerPoint Presentation

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Uploaded On 2020-04-03

Updates in Diffuse Large B-Cell Lymphoma - PPT Presentation

Program Goals DLBCL Subtypes 2008 WHO Classification Other DLBCL Variants Dissecting DLBCL into Molecularly and Clinically Distinct Subgroups by Gene Expression Profiling Outcomes Based on DLBCL Subtype Using Gene Expression Profiling ID: 774803

dlbcl cont references patients dlbcl cont references patients lymphoma therapy aggressive subtypes abbreviations chemotherapy outcomes dose expression profiling elderly

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Presentation Transcript

Slide1

Updates in Diffuse Large B-Cell Lymphoma

Slide2

Program Goals

Slide3

DLBCL Subtypes 2008 WHO Classification

Slide4

Other DLBCL Variants

Slide5

Dissecting DLBCL into Molecularly and Clinically Distinct Subgroups by Gene Expression Profiling

Slide6

Outcomes Based on DLBCL Subtype Using Gene Expression Profiling

Slide7

Efficacy of Bortezomib in Combination With Chemotherapy in DLBCL Subtypes

Slide8

Efficacy of R2CHOP in Newly-Diagnosed DLBCL Subtypes

Slide9

Ibrutinib In Relapsed/Refractory DLBCL

Slide10

Possible Methods to Improve Outcomes in DLBCL

Slide11

Treatment-Related Deaths and Prephase Therapy in Elderly DLBCL Patients

Slide12

Adjuvant Radiotherapy After CHOP-R For Patients With Bulky Disease

Slide13

Deauville Criteria

Slide14

Using PET/CT to Predict Outcomes in Patients With PMLBCL

Slide15

Response-Adapted Therapy

Slide16

Interim PET-Directed Therapy in Advanced DLBCL

Slide17

Chemotherapy Plus Autotransplantation in Patients With Aggressive Lymphoma

Slide18

Dose-intense Chemotherapy + Autotransplantation in Primary Therapy of Patients With Aggressive Lymphoma

Slide19

ASCT Shows Benefit in High-Risk Aggressive Lymphoma

Slide20

RICOVER-60 and SMARTE-R TrialsPharmacogenomics of Rituximab in Lymphoma

Slide21

SEXIE-R-CHOP-14Increased Dose of Rituximab In Elderly Males

Slide22

Characteristics of Double-Hit DLBCL

Slide23

Approach To Patients With DLBCL

Slide24

Concluding Remarks

Slide25

Abbreviations

Slide26

Abbreviations (cont)

Slide27

Abbreviations (cont)

Slide28

References

Slide29

References (cont)

Slide30

References (cont)

Slide31

References (cont)

Slide32

References (cont)

Slide33

References (cont)

Slide34

References (cont)

Slide35

References (cont)