PPT-PURINE BIOSYNTHESIS

Purines are biologically synthesized as nucleotides and in particular as ribotides ie bases attached to ribose5phosphate Purines are synthesized by two types of pathways the de novo pathways and the salvage pathways. DNA: Picture 51. http://info.bio.cmu.edu/courses/03231/ProtStruc/ProtStruc.htm. B-DNA: The advent of modeling. http://molvis.sdsc.edu/pdb/dna_b_form.pdb. 46 Å. . 12 base sequence. (1953-2003). DNA: Size, Shape & Self Assembly. OBJECTIVES:. Nomenclature of nucleic acids: . a. nucleosides*. . b. nucleotides. Structure . and function of . purines and pyrimidines. . Origin . of atoms in the purine . ring and in the pyrimidine ring.. nucleotides is essential for . life . processes. nucleotides . are the . activated precursors . of nucleic . acids. As such, they are necessary for the replication of the genome . an . adenine nucleotide, ATP, is . Purine catabolism. Purine degradation. Purine Salvage Pathway. From normal turnover of cellular nucleic acids. Obtained from the diet. Reutilization of adenine, hypoxanthine, and guanine. Two enzymes:. Metabolism. Dr. Anissa Atif Mirza. Synopsis. Fates of dietary Nucleoproteins/Nucleic Acids.. De novo Biosynthesis of Purines and Pyrimidines.. Salvage of Purines and Pyrimidines. Catabolism of Purines and Pyrimidines. OBJECTIVES:. Nomenclature of nucleic acids: . a. nucleosides*. . b. nucleotides. Structure . and function of . purines and pyrimidines. . Origin . of atoms in the purine . ring and in the pyrimidine ring.. Debarati Basu. Cell Wall Seminar. Outline. What genes involved in cellulose biosynthesis? . Which compartment is involved in cellulose biosynthesis? . What are the protein components of the cellulose syntheses machinery and how they are coupled in the cytoskeleton?. One of the important specialized pathways of a number of amino acids is the synthesis of purine and pyrimidine nucleotides. . These nucleotides are important for a number of reasons. Most of them, not just ATP, are the sources of energy that drive most of our reactions.. Longyun Guo. 1. John Morgan. 1,2. 1. Department of Biochemistry. 2. Davidson School of Chemical Engineering. Purdue University. May 2, 2019. Background. Lignin is an essential biopolymer in plant secondary cell walls . Dr. Anissa Atif Mirza. Synopsis. Fates of dietary Nucleoproteins/Nucleic Acids.. De novo Biosynthesis of Purines and Pyrimidines.. Salvage of Purines and Pyrimidines. Catabolism of Purines and Pyrimidines. Met.. Purine. Met.. Learning Objectives. 1. How . Are Purines Synthesized? . 2. . How Are Purines Catabolized?. 3. . How Are . Pyrimidines. Synthesized and . . . Catabolized. ?.  . 4. . How Are . Most cells actively turnover their. N.A.’s. especial RNA’s. This results in . the release . of adenosine, adenine, guanine. and . hypoxanthine. These are recovered. thru . salvage pathways. . or Biosynthesis . Microorganisms . can obtain . energy. in many ways, much of this energy is used in biosynthesis or . anabolism. . During biosynthesis, . m.o. begins with . simple . precursors. , such . Metabolic relationship of Amino Acids. Biosynthesis of Amino Acids. The carbon skeletons of many amino acids may be derived from metabolites in central pathways, allowing the biosynthesis of some, but not all, the amino acids in humans.