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Selecting Therapy for Relapsed/ Selecting Therapy for Relapsed/

Selecting Therapy for Relapsed/ - PowerPoint Presentation

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Uploaded On 2017-06-07

Selecting Therapy for Relapsed/ - PPT Presentation

Refractory Multiple Myeloma Case 1 Monitoring PostASCT Blood Testing Other Monitoring After Initial Therapy Case 1 cont Assessment at Relapse Symptomatic First Relapse Cytogenetic Testing at Relapse ID: 556975

therapy dex abbreviations relapse dex therapy relapse abbreviations cont len bor daratumumab phase trials testing carfilzomib monitoring case placebo

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Presentation Transcript

Slide1

Selecting Therapy for Relapsed/Refractory Multiple MyelomaSlide2
Slide3

Case #1Slide4

Monitoring Post-ASCTBlood TestingSlide5

Other Monitoring After Initial TherapySlide6

Case #1 (cont)Slide7

Assessment at RelapseSymptomatic First RelapseSlide8

Cytogenetic Testing at RelapseSlide9

Therapy Selection ConsiderationsSlide10

Recent Phase 3 Trials in R/R MMSlide11

ASPIRE

Len/Dex ± CarfilzomibSlide12

TOURMALINE-MM1Ixazomib + Len/Dex vs Placebo + Len/DexSlide13

ELOQUENT-2

Len/Dex ± ElotuzumabSlide14

POLLUX

Len/Dex ± DaratumumabSlide15

CASTORBor/Dex ± DaratumumabSlide16

ENDEAVOR Carfilzomib/Dex vs Bor/DexSlide17

PANORAMA-1Panobinostat/Bor/Dex vs Placebo/Bor/DexSlide18

Recent Phase 3 Trials in R/R MMSlide19

Other Issues to ConsiderSlide20

Special Safety ConsiderationsSlide21

Role of Second ASCT in First RelapseSlide22

Select Emerging Agents in MMSlide23

Key TakeawaysSlide24

AbbreviationsSlide25

Abbreviations (cont)Slide26

Abbreviations (cont)