PPT-Name Of Eicosanoids Eicosanoids

is a Generic term for the 20 Carbon related compounds like Prostaglandins PGs Prostacyclins PGI2 Thromboxanes TX Leukotrienes LT Lipoxins LX Resolvins Eoxins Biosynthesis Of Eicosanoids.  . Arthritis, Dermatitis, Migraine. Osteoarthritis (OA).  . -involves swelling of the joints.  . -overweight – causes wear of cartilaginous surfaces.  . -such wear results in loss of chondroitin sulphate and glucosamine which are carbohydrate polymers. Dr. . Haitham. M. Al-. Wali. P. h. .D. Pharmacology. 22 February 2018. 1. PROSTAGLANDINS. The NSAIDs act by inhibiting the synthesis of prostaglandins. Thus, an . understanding of . NSAIDs requires comprehension of the actions and . PGs, TXs, LTs). Objectives:. . Discover and distinguish relationships between . different types of eicosanoid molecules . (PGs, TXs, LTs). Gain knowledge of enzymes that create PGs . and TXs (COX-1 and -2). that include:. prostaglandins, thromboxanes, . leukotrienes. , & related compounds. . . They are generated from . phospholipid. precursors. . They function primarily as hormone-like chemical signals between cells.. Eicosanoids. Several Classes of Signal Molecules:. . P. rosta. g. landins, Thromboxanes, Leukotrienes. Produced In Almost all Tissues. Wide Range of Responses. Local Hormones. Very Potent. Short Half Life . SUHAS AGEY. Asst professor, . Dept of Pharmacology. Hrpiper, Shirpur. Contents . Introduction. Chemistry, biosynthesis . COX pathways . Prostaglandins . Classification . P’cological and patho. role.