PPT-piRNA Detection Via Multidimensional Small RNA Clustering

Presented by Stephanie Schustermann Supervisors Prof Eitan Bachmat Dr Alal Eran Mr Amitai Mordechai Faculty of Natural Sciences The Department of Computer Science BenGurion University of the Negev. Adapted from Chapter 3. Of. Lei Tang and . Huan. Liu’s . Book. Slides prepared by . Qiang. Yang, . UST, . HongKong. 1. Chapter 3, Community Detection and Mining in Social Media.  Lei Tang and Huan Liu, Morgan & Claypool, September, 2010. . Andrey Ivanov, Senior Policy Advisor, UNDP BRC. Eschborn. , 14 July 2013. Acknowledgements. This presentation summarizes some preliminary results of an ongoing research based on the data come primarily from . algorithm and its application in single . cell . RNA-. seq. data analysis and identification of gain or loss of functions of somatic mutations . Chi Zhang, Ph.D.. Center for Computational Biology and Bioinformatics. issue in . computing a representative simplicial complex. . Mapper does . not place any conditions on the clustering . algorithm. Thus . any domain-specific clustering algorithm can . be used.. We . What is clustering?. Why would we want to cluster?. How would you determine clusters?. How can you do this efficiently?. K-means Clustering. Strengths. Simple iterative method. User provides “K”. Lecture outline. Distance/Similarity between data objects. Data objects as geometric data points. Clustering problems and algorithms . K-means. K-median. K-center. What is clustering?. A . grouping. of data objects such that the objects . microRNA. . siRNA. . piwiRNA. 2. Homework (part. 1, watching . assignment). . www.massachusetts.edu/mello/index.html. https://www.youtube.com/watch?v=. 5ZE7o_bRekk. (Video for HW#1). Write . down all important and interesting facts on . Ship Smart Inc. is a small moving company near me that offers a variety of services to accommodate your specific requirements. Visit: https://www.shipsmart.com/small-move Ship Smart Inc. is a first-class small movers near me that offers hassle-free and affordable small moving services. Visit: https://www.shipsmart.com/small-move 1. Mark Stamp. K-Means for Malware Classification. Clustering Applications. 2. Chinmayee. . Annachhatre. Mark Stamp. Quest for the Holy . Grail. Holy Grail of malware research is to detect previously unseen malware. Fig1piRNAbiosynthesismechanismWithinthenucleustwotypesofpiRNAclustersaretranscribedtoproducetheprimarypiRNAsZucanditsco-factorsincisedprimarypiRNAsproducingpiRNAintermediateswitha52uracilinYbbodypiRNA and the usage of them in antiviral immunity . Heleri Kirsip. Bioinformaatika. JC. 10.11.2016. Mis. on . endogeenne. . viiruslik. element (EVE)?. Endogeensed viiruslikud elemendid – viiruse g. enoom. Produces a set of . nested clusters . organized as a hierarchical tree. Can be visualized as a . dendrogram. A . tree-like . diagram that records the sequences of merges or splits. Strengths of Hierarchical Clustering. Chan M, Lee N, Chan P, To K, Wong R, Ho W, et al. Seasonal Influenza A Virus in Feces of Hospitalized Adults. Emerg Infect Dis. 2011;17(11):2038-2042. https://doi.org/10.3201/eid1711.110205.