PPT-DNA damage, repair and recombination

MUTAGENESIS DNA DAMAGE DNA REPAIR RECOMBINATION MUTAGENESIS Mutations Mutations are heritable permanent changes in the base sequence of DNA Point mutations may be transitions eg GCAT or . Enter CPR® – Cell Phone Repair Franchise Systems, Inc. (CPR®) – an independent service organization dedicated to the on-premises repair of cell phones, iPods, and electronic devices at all of our locations from Yukon, OK, to Los Angeles, CA. Enter CPR® – Cell Phone Repair Franchise Systems, Inc. (CPR®) – an independent service organization dedicated to the on-premises repair of cell phones, iPods, and electronic devices at all of our locations from Yukon, OK, to Los Angeles, CA. Gil . McVean. There are no new questions in population genetics. …only new types of data. Genome sequences of entire populations. Data with linkage to deep phenotype information. Data from multiple species. Lecture . 26. th. Alexei Fedorov, 2014. Origin of Chess. http://www.expert-chess-strategies.com/who-invented-chess.html. http://www.ponderabout.com/archives/972/mind-boggling-exponential-growth.aspx. Alexei Fedorov. Recombination is an intrinsic property of nucleic acids and these molecules are susceptible to joining their ends. .. Evolution invented thousands of proteins that assist DNA recombination and became crucial for cell functioning. . Dr. Kevin Ahern. Structure. Structure. Structure. One Strand of DNA. Structure. Introduction. Structure. Introduction. DNA Structure. DNA Forms. Semi-Conservative Replication. Discontinuous. Replication. and repair. Rebecca Fry, Ph.D.. DNA damage. DNA damage, due to environmental factors and normal metabolic processes inside the cell, occurs at a rate of 1,000 to 1,000,000 molecular lesions per cell per day. . Program Overview . Discussion Outline. DNA Repair. ABCs of DNA Repair. DNA Repair Defects in Cancer. DNA Repair Defects Can Be an Achilles' Heel. Synthetic Lethality and Cancer DNA Repair Defects. Increased Sensitivity of . Principles of Molecular Biology. Group Members. Maira Aleem. Bilal Naveed. Tanzeela Raza. Maheen. Malik. Zaigham. Abbas. DNA Structure. DNA = Deoxyribose nucleic . acid.. Four Nucleotides . - A. denine. DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock of intense freckling and high melanoma incidence, related to UV sensitivity. The syndrome actually results from defects in any of nine genes involved in repair of UV damage. C. EPAIRING DAMAGED OR CORE View metadata, citation and similar papers at core.ac.uk provided by University of Birmingham Research Portal Targeting DNA repair for anti-cancer therapy Thomas Helleday1,2,*, Cecilia Lundin, Be A one-step DNA repair process involving an enzyme that reverts the DNA lesion to the original nucleotides. Examples are 0 6 -methylguanine DNA methyltransferase (MGMT) andphotolyases. MGMT Pairs of allelic genes may exchange chromosomal locations( genetic elements can move, both between chromosomes and within them.) by a process known as genetic recombination.. Homologous recombination .