PPT-Proteomics investigation into cardiac endothelial cells usi

Orbitrap at the Proteomics facility of the University of Stellenbosch Salome Smit Central Analytical Facility University of Stellenbosch Overview Proteomics analysis of cardiac endothelial cells. lecture 2. Dr. Heyam Awad. FRCPath. Cellular events. Inflammation,,,,,, recruitment and activation of leukocytes.. These leukocytes ingest offending agents but also produce mediators capable of tissue destruction. Pamela BL. Introduction . The cardiac muscle forms the muscular wall of the heart that is it forms the myocardium.. Some of the cardiac muscle is also present in the walls of the aorta, pulmonary vein and superior vena cava.. Manar. . Hajeer. , MD, . FRCPath. Margination. , rolling and . adhesion.. Transmigration between endothelial . cells.. Migration in the . interstitium. toward the site of stimulus (. chemotaxis. and activation) . Sri Venkateswara Institute of Medical College. Tirupathi. SHOCK. Shock is characterized by . systemic hypotension . due to either reduced cardiac output or reduced effective circulating blood volume. Embryonic development from endothelial precursors called ‘. angioblasts. ’. Angiogenesis/ neovascularization:. Process of blood vessel formation in adults . By branching and extension of adjacent blood vessels and . The Ohio State University, Columbus OH USA. Wenyuan Yin. 1. , Daniel B. McKim. 1. , Caroline M. Sawicki. 2. ,. . Michael D. Weber. 1. , John F. Sheridan. 1,2. , Jonathan P. Godbout. 1. Endothelial cells modulate immune-brain signaling after psychosocial stress. hCMEC. /D3 cells. The TEM shows one astrocyte in direct contact with the endothelium. . Scale bar = 2. μ. m.. Endothelium. Astrocyte. Collagen gel. Supplementary figure 2. Transmission electron micrograph of . Cells and . Blood Cells/Factors. Intercellular/Cell-Surface Elements. Selective alteration/dysregulation . of junctional proteins (. Claudins. , . . Occludin. , JAM, ...). Cell Adhesion proteins (E-Selectin, . Corresponding author: Review ArticleJournal of Blood & Lymph Journal of Blood & LymphISSN: 2165-7831 Volume 8  Issue 2  1000221J Blood Lymph, an open access journalISSN: 2165-7831 Page 2 of 6 e Assistant Professor of Pathology. Pathology Department . University of Jordan. Normal blood vessel histology. Artery (A) . vs. . vien. (V) . The thickness of the tunica media is larger in arteries than in veins because blood pressure inside them is higher and to pump blood to down stream tissues (the tissues supplied by this artery). Professor and HOD. Department of Pathology. OVERVEIW. DEFINITION OF ATHEROSCLEROSIS. RISK FACTORS. HYPOTHESIS REGARDING PATHOGENESIS. COMPLICATIONS. CLINICAL MANIFESTATIONS. ATHEROSCLEROSIS. Atherosclerosis means . Ryan Fellers, Proteomics Center of Excellence. OSG All Hands Meeting, 3/24/2015. Agenda. Introduction to Proteomics. What is it?. Top Down Proteomics specifics. Tools . and Support. Legacy of Tool Development. _The wall of a segment of capillarity may be formed by a single endothelial cell. . _Only tunica intimae is present ,which typically consist of the endothelium, its basal lamina and an in complete layer of cells surrounding the capillary, the pericytes. . Leukocyte Migration . And Scientific Writing. Sailasya. . Gundlapudi. BNFO 301. https://lasyagundlapudi.wixsite.com/leukocytemigration. How does anything reach the brain? . Important decisions are made in the brain .