PPT-Clinical Benefit of Integrative Genomic Profiling

in Advanced Solid Tumors EDRN Biomarker Development Lab Arul M Chinnaiyan MD PhD American Cancer Society Research Professor Howard Hughes Medical Institute Sequencing Buccal swab or Blood. Dr. Ashwinikumar A. Raut . MD (. Ayurveda-Kayachikitsa). Director Clinical Research & Integrative Medicine. Medical Research Centre of Kasturba Health Society. ICMR Advanced Centre of Reverse Pharmacology in Traditional Medicine. Presented by: Bryan Shaw. Background. TIL are a part of tumors and are well know to have major roles in cancer biology. TIL are vital in tumor growth, cancer progression and response to therapy.. Figure 1. Current and emerging techniques for evaluating TIL composition in solid tumors.. Motivation and Inspiration. Green ED, Guyer MS. . . Nature . 2011; 470:204-13.. How are we going to do this?. What is actually going on in the field?. What role should NIH/NHGRI play to support and accelerate progress? . 19 May 2014. Jim Evans MD, . Ph.D. University of North Carolina at Chapel Hill. Accomplishments, Challenges and Opportunities. Green & . Guyer. . Nature; 470:204.2011. Medical Science = Clinical Care. Implementation Framework Toward a National Genomic Surveillance NetworkExecutive SummaryThe rapid emergence and spread of SARS-CoV-2 make clear the need for robust systems to detect and track viral t ForewordOne secret weapon has helped beat every disease outbreak over the last century but it is not masks or social distancing lockdowns or even vaccines Instead it is data Data tells us which masks (Abstract 58). J.B. Cole. 1,*. K.L. Parker Gaddis. 2. , C. Willard. 1. , D.J. Null. 1. , C. Maltecca. 3. , and J.S. Clay. 4. 1 . Animal Genomics and Improvement Laboratory, ARS, USDA, Beltsville, MD, USA. Programme. and can be adapted and used for local education and training about the patient choice consent model being implemented for whole genome sequencing in the NHS Genomic Medicine Service. . Please note that this does not address . Skin SSG . May 2018. Catherine Carpenter-Clawson, Programme Manager, WE GMC. Courtesy of Genomics England. From . Genetics . to . Genomics. Genetic testing = single gene. (. s. ). or panels. . Exome sequencing = coding DNA . Laura Yarram-Smith. SWGLH Solid Tumour Laboratory Lead. 20/09/2019. Breast Cancer Genomics. Genomics in England and Genomic Lab Hub. Genomic Test Directory. Genomic Biomarkers in Breast Cancer. Future technologies . Louise Medley. Consultant Medical Oncologist & Cancer Clinical Lead SW GLH. SWAG OG CAG March 24. th. 2023. WHY?. Prevention. Early Diagnosis. Neo-adjuvant . Adjuvant . Palliative. Living with Cancer . John Kenny. Centre for Genomic Research, University of Liverpool.. CGR. CGR. Experimental Design, Bioinformatics.. Library production/sequence generation:. RNA-Seq, . SAGE, . Fragment, . Mate-pair, . Chris Wragg, Lead Cancer Scientist, SWGLH. 6. th March 2019. Contents. 100,000 Genomes Project. National update. Update on the future genomic medicine service. National delivery of 100,000 . Genomes . Working together towards a common strategy . Overview. Implementing Genomic Medicine. Vision. Scope & Purpose. Background. SNOMED CT Strategy . (what & how). Strategic objectives. Next steps.