PPT-LO 3.36: The student is able to describe a model that expresses the key elements of signal

LO 336 The student is able to describe a model that expresses the key elements of signal transduction pathways by which a signal is converted to a cellular response SP 15 The student can reexpress key elements of natural phenomena across multiple representations in the domain. Chapter 13, . Stryer. Short Course. Signal Transduction. Signal from exterior of cell must affect interior of cell. Through the membrane. Amplification of signal. Ability to turn off. A few pathways…. . Enzyme-linked . receptors. Nuclear receptors. Stochasticity. in . signalling. .. Enzyme-linked receptors. . signalling. through growth factors, hormones, cytokines. acting locally at very low concentrations (10. VOCABULARY. directions: mark each term to indicate if you know it, are unsure, or don’t.. amplify . communication. deleterious elaborate. embryology evolution . fluid . mosaic model mechanism. Organisms. can function normally only if:. All the cells of their different organs communicating effectively with their surroundings. . Once a cell picks up a hormonal or sensory signal, it must transmit this information from the surface to the interior parts of the cell—. Pratt & . Cornely. , Chapter 10. Terms for Signal Transduction. Ligand. Receptor. Transducer. Effector. Second messenger. Target proteins/DNA. Ligands. Hormones vs Local mediators. Polar (insulin) vs nonpolar (steroidal hormone). . Signal Transduction Pathway. EXTRACELLULAR. FLUID. Plasma membrane. CYTOPLASM. Receptor. Signaling. molecule: ligand. Relay molecules in a signal transduction pathway. Activation. Pratt & . Cornely. , Chapter 10. Terms for Signal Transduction. Ligand (first messenger). Receptor (transducer). Primary Effector. Second . messenger. Second effector, etc.. Target proteins/DNA. Ligands. Signal transduction . General features of signal transduction. Type of cell signalling. Type of Signal . transducer/Receptors. signal transduction. T. he . signal. . represents the information, . that is detected by specific . Ligand-Receptor Interactions. Cell and Developmental . Biology Group. Goals – . Integration of quantitative skills in cell biology. Modeling cellular responses .  . Class setup. First or second year majors in cell biology. . Enzyme-linked . receptors. Nuclear receptors. Stochasticity. in . signalling. .. Enzyme-linked receptors. . signalling. through growth factors, hormones, cytokines. acting locally at very low concentrations (10. More than 4 years experience in developing and analyzing mathematical models of complex bio-chemical reaction networks 10 Journal papers, 1 book chapter, 6 peer-reviewed conference papers, and 7 transduction can alter cellular response.. SP 1.5. : The student can . reexpress. key elements of natural phenomena across representations in the Domain . Explanation. : A signal transduction pathway is where signal transduction occurs. Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. Receptor then causes a chain of event with in the cell, causing a cellular response. Signal transduction pathways can be altered. Signal transduction pathways can be blocked by the use of drugs such as antihistamines. Also signal transduction pathways being blocked can act as a preventative against diseases. A more specific impact of drugs altering cellular response is antihistamines. This changing signal transduction is how the antihistamines block transduction by blocking the histamine that is released by the cells immune system. When a foreign antigen binds to the . Cellular Signaling. Autocrine Signals . Diffuse from one part of a cell to another part of the same cell. Synaptic signaling. Neurotransmitter is the signaling molecule. Occurs in the animal nervous system. Outline. Review of Photosynthesis. Finish up Cam plants . Cell-Cell Communication. Local vs Long distance. Three Stages of Signaling. Reception. Transduction. Response. Photosynthesis - Overview. “Fixing” Carbon.