PPT-Rearrangement vs. Point Mutations

By Karl Menzel Is rearrangements or Point Mutations Faster Synteny Blocks and Chromosomes Mouse Human Chimp Human Data Reading and Sliding Window Human vs Chimp Human vs Mouse. What Are Mutations?. Mutation: . Changes . in the nucleotide sequence of . DNA. Mutagen: . A physical or chemical agent that changes DNA. Mutation May . occur . in:. somatic cells (body cells): . will not be . What happens if there is a mistake (. mutation. ). in the DNA code?. Possibly proteins won’t be made or are made improperly.. If the mutations occur in the gametes, the offspring’s DNA will be affected positively, negatively, or neutrally.. http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Changes in the genetic material. Mutations can occur in two different types of Cells:. 1. Somatic (body) cells. 2. Gamete (sex or germ) cells. Mutations in somatic cells. Usually result in killing that body cell only.. Given a mutation, identify its type. Predict how a mutation will affect a protein.. Mutations. Changes in genetic material (DNA). 2 main types of mutations. Point mutation- change in one or a few nucleotides (letters). How does it happen???. Environmental Influences . such . as: . Chemicals or UV Rays. Inherited: mutations can be passed down from . parent. to . offspring. During copying of . DNA. , . mistakes. can occur. Small-scale mutations. Missense mutations. Nonsense mutations. Silent mutations. Frameshift mutations. Large scale mutations. Causes. Mutagens. The results of mutation. Mutations. Genetic mutations are changes in the DNA sequence, caused by various mechanisms.. MISTAKES IN DNA. A MISTAKE CAN BE:. 1. A point mutation – substitution, addition, or removal of a single DNA base.. 2. A . frameshift. mutation – . a point mutation due to an addition . or deletion of a DNA base that causes a major change in the genetic code.. KEY CONCEPT:. . Mutations. are changes in genetic material.. VOCABULARY:. Mutation, point mutation, . frameshift. mutation, polyploidy. Mutations – extension from gene expression. . Changes in genotype. Science. Learning intention. To understand the different types of mutations. . You will need. A pen and a piece of paper or a laptop to record your answers. . You may need the internet to search for answers. . . Dr. Geeta Singh. Assistant Professor. Department of Chemistry. D.D.U. Gorakhpur University, Gorakhpur. 1. . Introduction. Pinacol-Pinacolone Reaction. Mechanism of Pinacol-Pinacolone Reaction. Examples of Pinacol-Pinacolone Reaction. Dr. Geeta Singh. Assistant Professor. Department of Chemistry. D.D.U. Gorakhpur University, Gorakhpur. 1. . CONTENTS. History . of Hoffmann. Hoffmann . Rearrangement. Mechanism. mutation. Mutations. Actual Mutations . in fruit flies. What is a mutation?. A mutation is any change in a cell’s DNA. A mutation can occur in an individual gene. - results in a single changed protein. mutation. Mutations. Ectrodactyly. Progeria. Hypertrichosis. Severe Combined Immunodeficiency Disorder (SCID). Sickle Cell Anemia. Heterochromia. iridium. What is a mutation?. @A . mutation is any change in a cell’s .