PPT-DNA Mutations Biology Chapter 10

How does it happen Environmental Influences such as Chemicals or UV Rays Inherited mutations can be passed down from parent to offspring During copying of DNA mistakes can occur. Mutations. What is a mutation?. A change in DNA. Can cause changes in organism. Happen randomly. Can be beneficial, neutral, or harmful. For example, the golden color on half of this Red Delicious apple was caused by a mutation in its body cells. Its seeds (reproductive cells) will not carry the mutation. .  . Student Learning Goals - Biology. Science and Life. SC.912.N.1.1. Goal. :. . Define a problem based on a specific body of knowledge, for example: biology, chemistry, physics, & earth/space science. . http://faculty.uca.edu/~johnc/mbi1440.htm. http://www.wappingersschools.org/RCK/staff/teacherhp/johnson/visualvocab/mRNA.gif. GENETIC MATERIAL . In the middle of the 1900’s scientists were asking questions about genes.. http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Point mutations. single base change . silent mutation. no amino acid change. redundancy in code. missense. change amino acid. Changes the final protien. nonsense. change to stop codon. Stopping prematurely . The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet. . If we change the sequence of the letters do we change the nature of the message?. That . DNA. Deoxyribonucleic Acid (DNA). The genetic material. Contains the “blueprint” for an organism. Instructions for an organism’s traits. Nucleic Acid-polymer (chain) of nucleotides (monomers). Very long molecule. Asst. Prof. Dr. . Dalya. Basil Hanna . In this lecture…... Mutation:. Gene (point) Mutation. Chromosomal Mutation. Gene Mutation . A gene mutation occurs when the nucleotide sequence of the DNA is altered and a new sequence is passed on to the offspring. The change may be either a substitution of one or a few nucleotides for others or an insertion or deletion of one or a few pairs of nucleotides. Etienne GC . Brain. , MD . PhD. Institut Curie. Saint-Cloud. , France. www.siog.org. etienne.brain@curie.fr. 1. 2. Cancer . paradox. … is frequent. Total . life risk:. 1/2 . for men. . 1/3 for women. Main idea: Gene expression is regulated by the cell, and mutations can affect this expression. Gene Regulation . Cells have the ability to control which genes are transcribed and when they are transcribed. Abhinandan. . Chowdhury. (. ACh. ). Lecturer. Dept. Biochemistry & Microbiology. North . South University. Dhaka, . Bangladesh. Email; . abcnsuedu@gmail.com. Website: . www.abhinandanchowdhury.weebly.com. Sylvia Plevritis, PhD. Course Director. Melissa . Ko. Teaching Assistant. Fuad. . Nijim. CCSB Program Manager. March 31, 2014. Goals of CBIO243. Introduce major principles of cancer systems biology that integrate experimental and computational biology.. Aravinda . Chakravarti. , PhD. Center for Complex Disease Genomics . Johns Hopkins University School of Medicine. Disclosures: . Biogen. Idec (SAB). Brainiacs. : Recent Advances in Neuroscience. 2014 IBBS Science Writer’s Workshop. DNA . mutations and . repair. mechanisms. Mamoun Ahram. , PhD. 1. Mutations. What are mutations?. A mutation is a change in the genetic material.. Somatic mutations occur in somatic cells and are not transmitted..