PPT-Mutations Mutations overview
Author : elyana | Published Date : 2022-06-07
Smallscale mutations Missense mutations Nonsense mutations Silent mutations Frameshift mutations Large scale mutations Causes Mutagens The results of mutation Mutations
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Mutations Mutations overview: Transcript
Smallscale mutations Missense mutations Nonsense mutations Silent mutations Frameshift mutations Large scale mutations Causes Mutagens The results of mutation Mutations Genetic mutations are changes in the DNA sequence caused by various mechanisms. Changes in . DNA. that affect genetic information. Gene Mutations. Point Mutations – changes . in one or a few. nucleotides. Substitution. THE FAT CAT ATE THE RAT. THE FAT HAT ATE THE RAT. Insertion. What Are Mutations?. Mutation: . Changes . in the nucleotide sequence of . DNA. Mutagen: . A physical or chemical agent that changes DNA. Mutation May . occur . in:. somatic cells (body cells): . will not be . Mutations. Any unpredictable change in the structure or amount of DNA of an organism is called a . mutation. . . Most . mutations occur in . somatic (body) cells. and are not passed from one generation to the next. . By Karl . Menzel. Is rearrangements or Point Mutations Faster. Synteny. Blocks and Chromosomes. Mouse Human. Chimp Human. Data Reading and Sliding Window. Human vs Chimp. Human vs Mouse. Mutation. Permanent change in the genetic material of an organism. All mutations in gametes are inheritable because they are copied during DNA replication. Somatic cell mutations occur in body cells. P Ferguson, L . Quek. , M . Metzner. , I Ahmed, C Garnett, S Jeffries, K . Piechocki. , R Danby, M . Raghavan. , A . Peniket. , M Griffiths, A Bacon, J Ward, K Wheatley, P Vyas, C Craddock. Introduction. Jessica Hawley. Compiled . By: . C. Kohn, Waterford, WI. Objectives. Identify and analyze impacts of mutation.. Interpret impacts of mutation.. Analyze genetic information to determine mutations.. Work on SAE Record Books.. >2500 cancer genomes: Overall . functional . impact. Slides freely . downloadable . from . Lectures.GersteinLab.org. . & “tweetable” . (via . @. markgerstein. ). . See last slide . for more info.. What happens if there is a mistake (. mutation. ). in the DNA code?. Possibly proteins won’t be made or are made improperly.. If the mutations occur in the gametes, the offspring’s DNA will be affected positively, negatively, or neutrally.. Polypeptides made up of amino acids. Proteins are polypeptides, numerous amino acids. First Recall Proteins------. **Peptide Bond between amino acids. **Notice the “R” group. It’s a group of molecules that determines the amino acid.. Nobody’s perfect all the time . About 1/10 billion base pairs end up with a error or mutation . Mutation: Mistake in DNA replication or an environmental effect that . results. in a change to the nitrogenous bases in DNA or RNA. . Changes in the genetic material. Mutations can occur in two different types of Cells:. 1. Somatic (body) cells. 2. Gamete (sex or germ) cells. Mutations in somatic cells. Usually result in killing that body cell only.. The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet. . If we change the sequence of the letters do we change the nature of the message?. That . mutation. Mutations. Actual Mutations . in fruit flies. What is a mutation?. A mutation is any change in a cell’s DNA. A mutation can occur in an individual gene. - results in a single changed protein.
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