PPT-Regulation of ORMDL3 Gene Expression through the ERK/CREB Pathway

Annie Vo ORMDL3 Orosomucoid 1like 3 Associated with onset of childhood asthma Expressed in bronchial epithelial cells Encodes a transmembrane protein Pump that regulates calcium ions into the . Inducible gene expression. kinetics of . β-galactosidase. enzyme induction. Add inducer. start transcription = mRNA accumulation. mRNA translation = protein accumulation. Remove inducer. Stop. transcription (. of gene expression. . References:. . Stryer. : “Biochemistry”, 5. th. Ed.. Hames. & Hooper: “Instant Notes in Biochemistry”, 2. nd. Ed.. 1. Basic principles of gene control. What is gene expression?. What does the operon model attempt to explain?. the coordinated control of gene expression . in bacteria. bacterial resistance to antibiotics. how genes move between homologous regions of DNA. the mechanism of viral attachment to a host cell. Adam Stevens, Daniel Hanson, Andrew . Whatmore. , Benoit . Destenaves. , Pierre . Chatelain. , Peter . Clayton. Supplementary Information: . Introduction. In this Supplementary Information we make available additional data that were discussed in the main manuscript. . Gene Expression Group. 7/14/11. 2011 National Academies Northstar Institute for Undergraduate Education in Biology . Outline. Context. Review: Clicker Questions. Cell Differences (Think-Pair-Share). Regulation of Gene Expression (Mini-Lecture). Outline. Objective. Mechanism. K. inase cascades and Phosphorylation/. dephosphorylation. . General. Learning/LTP. Synaptic strengthening. Control of gene expression. Transcription factors. Epigenetics. CSCOPE. Unit: 08 Lesson: 01. There are hundreds of different types of cells in your body, and each type has a unique function. We’re going to compare some different types of cells to see how much they have in common. . Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. The cerebellum is the region of the brain that coordinates motor control, and many human neural disorders impact the cerebellum.. Several spontaneous mouse mutants with motor defects have been found, including:. (Chapter 9). Presented by Dr. Laurie M. Erickson. Chair of the Department of Health Sciences. Blitstein Institute of Hebrew Theological College. Chicago, IL, USA.. Gene Expression can be Regulated.. Gene expression: . . 1. The . trp. Operon. Contains 5 genes coding for proteins (enzymes) required for the synthesis of the amino acid tryptophan. Also contains a promoter and operator.. When tryptophan levels in the cell are low, the expression of the . Systematic . In . silico. . analysis using public database. Sung Hwan Lee. 1,4. , Baek Gil . Kim. 2,3. , . Ho Kyoung Hwang. 1,4. , Woo . Jung . Lee. 1,4. , Chang . Moo Kang. 1,4**.  . 1. Department . AP Bio – Ch. 16-21. Unit 6 – Overview. Ch. 16 – The Molecular Basis of Inheritance (DNA). Ch. 17 – Gene Expression: From Gene to Protein. Ch. 18 – Regulation of Gene Expression. Ch. . 19 . – . Principles – Math Problems. Computation of solutions to Math Problems such as NP complete problems. Bacterial computers. We can encode these math problems in biological terms and solve prototype versions of them.