PPT-Innate Immunity

First Line of Host Defence Lea MuntheFog The Complement System is Activated by PAMPsDAMPS Lea MuntheFog Recognition of PAMPsDAMPs by Complement Receptors CRs Lea MuntheFog Phagocytosis. Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. All organisms have innate behaviors that are inherited from parents that develop independently from the environment. Innate behavior is inherited from an individual’s parents and is not modified by the individual and is generally not affected by the organism’s environment, including an organism’s experiences.. Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. In short, it is safe to state that immunity refers to the rules and principles that govern diplomatic relations between states and other entities with legal personality within the international system.. Cells of the Immune System. Physical & Chemical Barriers. Innate and Adaptive Immunity. Innate Defenses. Nonspecific physical and chemical barriers that contribute to resistance against infection. disease. Disease-any condition that impairs the normal functioning of the body. Violation of homeostasis. Homeostasis-ability of the body to keep proper internal conditions no matter what is happening outside of it.  . Immunity . is defined as the capacity of the body to resist the pathogenic agents. It is the ability of the body to resist the entry of . different types of . foreign bodies like bacteria, . virus, . The term Immunity has traditionally referred to the resistance exhibited by the host towards injury caused by microorganism and their product.. However, protection against infectious disease is only one of many consequences of immune response, which in its entirety is concerned with the reaction of the body against any foreign antigen.. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Dr. . M.A.Thomas. . FUNCTIONS . OF THE IMMUNE SYSTEM. :. Recognize. , destroy and clear a diversity of pathogens. .. Initiate . tissue and wound healing processes. .. Recognize . and clear damaged self components. of certain substances in . the blood and lymph stream. . These . substances are known as antibodies. . This immunity is inborn. . . Antigens. , the foreign substances that attack the body, stimulate the production of antibodies. . Features of adaptive immunity:. Adaptive immunity is characterized by the following:. 1. Antigenic specificity: (. highly specific).. 2. Diversity : . ( each antigen there is specific T-cell and B-cell for it).. Its . how your body recognizes and defends itself against bacteria, viruses, and substances that appear foreign and harmful.. IMMUNE SYSTEM- . Its a network of tissues and organs containing cells that recognize foreign substances in the body and destroy .